Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | MAT2A | P31153 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2334760 | 0.84 | NPSR1 (0.42) | NPSR1NOS3NOS2PLATADRB1 | |
| SCHEMBL2332470 | 0.77 | NPSR1 (0.35) | NPSR1NOS3NOS2PLATHCRTR1 | |
| SCHEMBL2336317 | 0.77 | NPSR1 (0.37) | NPSR1NOS3NOS2PLATSYK | |
| SCHEMBL2335764 | 0.77 | NPSR1 (0.37) | NPSR1NOS3NOS2SYKHCRTR1 | |
| SCHEMBL2338354 | 0.77 | NPSR1 (0.35) | NPSR1NOS3NOS2PLATADRB1 | |
| SCHEMBL2333905 | 0.76 | NPSR1 (0.39) | NPSR1NOS3NOS2PLATSYK | |
| SCHEMBL2341812 | 0.76 | ALDH1A1 (0.49) | NPSR1FAAHCES1ALDH1A1GAA | |
| SCHEMBL2338895 | 0.76 | GRIN1 (0.40) | PLATHCRTR1HCRTR2P2RX7CYP17A1 | |
| SCHEMBL2336622 | 0.75 | ALDH1A1 (0.39) | NPSR1NOS3NOS2PLATSYK | |
| SCHEMBL2340988 | 0.75 | SYK (0.40) | PLATSYKHCRTR1HCRTR2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215086-B1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL CO (JP) | 2011-08-24 | — | — | EP | disclosed |