SCHEMBL2334760

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2334759	0.84	NPSR1 (0.39)	NPSR1NOS3NOS2PTGS2PTGS1
	SCHEMBL2336317	0.81	NPSR1 (0.37)	NPSR1NOS3NOS2SYKABL1
	SCHEMBL2338354	0.81	NPSR1 (0.35)	NPSR1NOS3NOS2SYKGRIN1
	SCHEMBL2335764	0.81	NPSR1 (0.37)	NPSR1NOS3NOS2SYKABL1
	SCHEMBL2333905	0.80	NPSR1 (0.39)	NPSR1NOS3NOS2SYKABL1
	SCHEMBL2336622	0.79	ALDH1A1 (0.39)	NPSR1NOS3NOS2SYKGRIN1
	SCHEMBL2332470	0.78	NPSR1 (0.35)	NPSR1NOS3NOS2GRIN1GRIN2B
	SCHEMBL2332695	0.78	NPSR1 (0.40)	NPSR1SYKABL1BCRP2RX7
	SCHEMBL2335213	0.78	ALDH1A1 (0.36)	NPSR1SYKABL1BCRALDH1A1
	SCHEMBL2338895	0.77	GRIN1 (0.40)	GRIN1GRIN2BP2RX7PLATHCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.