Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 16/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335764 | 0.81 | NPSR1 (0.37) | SYKHCRTR1HCRTR2P2RX7 | |
| SCHEMBL2332580 | 0.81 | HPGD (0.40) | SYKHCRTR1HCRTR2P2RX7 | |
| SCHEMBL2332695 | 0.81 | NPSR1 (0.40) | SYKPLATHCRTR1HCRTR2P2RX7 | |
| SCHEMBL2333905 | 0.81 | NPSR1 (0.39) | SYKPLATHCRTR1HCRTR2P2RX7 | |
| SCHEMBL2338430 | 0.80 | HPGD (0.42) | SYKHCRTR1HCRTR2P2RX7 | |
| SCHEMBL13028269 | 0.79 | AKR1C3 (0.43) | SYK | |
| SCHEMBL2335213 | 0.79 | ALDH1A1 (0.36) | SYKHCRTR1HCRTR2 | |
| SCHEMBL2335387 | 0.78 | ALDH1A1 (0.38) | SYKHCRTR1HCRTR2 | |
| SCHEMBL2339420 | 0.78 | ALDH1A1 (0.38) | SYKHCRTR1HCRTR2P2RX7 | |
| SCHEMBL2342360 | 0.77 | NPSR1 (0.36) | SYKPLATHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318776-B2 | Pyridine compound, pesticidal composition and method of controlling pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-11-27 | — | — | US | disclosed |
| US-8318776-B2 | Pyridine compound, pesticidal composition and method of controlling pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-11-27 | — | — | US | disclosed |
| US-8318776-B2 | Pyridine compound, pesticidal composition and method of controlling pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-11-27 | — | — | US | disclosed |
| EP-2215086-B1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL CO (JP) | 2011-08-24 | — | — | EP | disclosed |
| US-20100286148-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100286148-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100286148-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286148-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | C5, PRDX1, PLPBP | SYK 1356/4885PLAT 3764/4885HCRTR1 787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.