SCHEMBL28547834

SCHEMBL28547834

CCCc1ccccc1C1OC(=O)COC1=O

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HTT P42858 1/20 0.32
CYSLTR2 Q9NS75 2/20 0.32
CYSLTR1 Q9Y271 2/20 0.32
ELANE P08246 1/20 0.31
GSK3B P49841 1/20 0.31
MAOA P21397 1/20 0.30
PLA2G6 O60733 2/20 0.30
PLA2G4A P47712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28548167 0.92 CYSLTR2 (0.38) KDM4EALDH1A1HTTCYSLTR2CYSLTR1
SCHEMBL28911291 0.90 ALDH1A1 (0.34) KDM4EALDH1A1HTTGSK3B
SCHEMBL28540507 0.77 TAAR1 (0.37) ALDH1A1
SCHEMBL28542554 0.74 TP53 (0.41) KDM4EALDH1A1MAOA
SCHEMBL28553683 0.74 MAPT (0.33) KDM4EALDH1A1
SCHEMBL28545968 0.74 MGLL (0.35) ALDH1A1PLA2G6PLA2G4A
SCHEMBL28546594 0.72 DRD2 (0.40) PLA2G6PLA2G4A
SCHEMBL9303316 0.70 ALDH1A1 (0.43) KDM4EALDH1A1HTT
SCHEMBL28547883 0.69 SPHK1 (0.38) ALDH1A1PLA2G6PLA2G4A
SCHEMBL28545946 0.67 MEN1 (0.38) KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553708-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553709-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553707-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2021-04-09 CN claimed
CN-109553708-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553709-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553707-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2021-04-09 CN disclosed