SCHEMBL23348332

SCHEMBL23348332

CC(C)(C)c1ccc2c(c1)c1ccc(C(C)(C)C)cc1n2-c1cc(C#N)cc(-n2c3ccc(C(C)(C)C)cc3c3ccc(C(C)(C)C)cc32)c1-c1c(F)cccc1F

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.32
RORC P51449 1/20 0.31
CSNK1D P48730 1/20 0.31
CSNK1G2 P78368 1/20 0.31
HTR1D P28221 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22156842 0.96 KIF11 (0.34) KIF11CSNK1DCSNK1G2
SCHEMBL22156846 0.95 KIF11 (0.35) KIF11RORCCSNK1DCSNK1G2HTR1D
SCHEMBL22156845 0.94 KIF11 (0.35) KIF11RORCCSNK1DCSNK1G2
SCHEMBL22156840 0.93 RORC (0.35) KIF11RORCCSNK1DCSNK1G2HTR1D
SCHEMBL23348329 0.91 EGLN2 (0.33) KIF11RORCCSNK1DCSNK1G2HTR1D
SCHEMBL23348408 0.91 KIF11 (0.35) KIF11
SCHEMBL23348406 0.86 KIF11 (0.36) KIF11RORCCSNK1DCSNK1G2HTR1D
SCHEMBL22156444 0.84 KIF11 (0.36) KIF11CSNK1DCSNK1G2
SCHEMBL23348383 0.84 KIF11 (0.38) KIF11CSNK1D
SCHEMBL23348327 0.84 KIF11 (0.35) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210139425-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-05-13 US disclosed
US-9527885-B2 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2016-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210139425-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CCND2, CCND1, CRY1 KIF11 1724/4885RORC 1165/4885CSNK1D 1514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.