Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.32 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 2/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23348444 | 0.93 | KCNH2 (0.32) | KCNH2KIF11 | |
| SCHEMBL23348543 | 0.89 | KCNH2 (0.36) | KCNH2KCNJ5KCNJ3KCNQ1CACNA1C | |
| SCHEMBL23348322 | 0.89 | KIF11 (0.33) | PGRKIF11 | |
| SCHEMBL23348315 | 0.88 | KIF11 (0.38) | KCNH2HTR1DRAPGEF3RAPGEF4PGR | |
| SCHEMBL23348299 | 0.88 | HTR1D (0.32) | KCNH2HTR1DPGRARKIF11 | |
| SCHEMBL23348503 | 0.87 | DHODH (0.33) | KCNH2HTR1DRAPGEF3RAPGEF4PGR | |
| SCHEMBL22156390 | 0.87 | KCNH2 (0.35) | KCNH2HTR1DRAPGEF3RAPGEF4PGR | |
| SCHEMBL23348405 | 0.86 | ALDH1A1 (0.36) | KCNJ5KCNJ3KCNQ1CACNA1CHTR1D | |
| SCHEMBL22158353 | 0.86 | KIF11 (0.36) | KCNJ5KCNJ3KCNQ1CACNA1CKIF11 | |
| SCHEMBL22156523 | 0.85 | KIF11 (0.31) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139425-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139425-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CCND2, CCND1, CRY1 | KCNH2 143/4885KCNJ5 2373/4885KCNJ3 1897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.