Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 6/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23348523 | 0.89 | CHEK1 (0.36) | CHEK1PTGER4EGLN2KDM1A | |
| SCHEMBL23348415 | 0.87 | ALDH1A1 (0.34) | CHEK1PTGER4ALDH1A1ATMAR | |
| SCHEMBL23348226 | 0.87 | SMN1; SMN2 (0.36) | ALDH1A1 | |
| SCHEMBL23348253 | 0.87 | EGLN2 (0.38) | EGLN2 | |
| SCHEMBL25659019 | 0.86 | PTGER4 (0.40) | CHEK1PTGER4ALDH1A1ATMEGLN2 | |
| SCHEMBL21928627 | 0.85 | CHEK1 (0.40) | CHEK1EGLN2ARTNKS2KDM1A | |
| SCHEMBL24737225 | 0.85 | CHEK1 (0.42) | CHEK1EGLN2ARTNKS2KDM1A | |
| SCHEMBL23348252 | 0.84 | EGLN2 (0.32) | EGLN2 | |
| SCHEMBL21928625 | 0.84 | CHEK1 (0.39) | CHEK1PTGER4ALDH1A1ATMEGLN2 | |
| SCHEMBL23348466 | 0.84 | CHEK1 (0.37) | CHEK1PTGER4ATMAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139425-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139425-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CCND2, CCND1, CRY1 | CHEK1 303/4885PTGER4 2435/4885ALDH1A1 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.