SCHEMBL23348253

SCHEMBL23348253

Cc1cc(C)c(-c2ccc3c(c2)c2ccc(-c4c(C)cc(C)cc4C)cc2n3-c2cccc(-n3c4ccc(-c5c(C)cc(C)cc5C)cc4c4ccc(-c5c(C)cc(C)cc5C)cc43)c2-c2c(F)cc(C#N)cc2F)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EGLN2 Q96KS0 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23348539 0.92 EGLN2 (0.33) EGLN2
SCHEMBL23348455 0.87 CHEK1 (0.37) EGLN2
SCHEMBL23348231 0.86 PGR (0.35) EGLN2
SCHEMBL23348237 0.85 CHEK1 (0.31)
SCHEMBL23348252 0.85 EGLN2 (0.32) EGLN2
SCHEMBL23348515 0.84 EGLN2 (0.34) EGLN2
SCHEMBL23348226 0.83 SMN1; SMN2 (0.36)
SCHEMBL23348234 0.82 PGR (0.33)
SCHEMBL23348415 0.81 ALDH1A1 (0.34)
SCHEMBL23348523 0.81 CHEK1 (0.36) EGLN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210139425-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210139425-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CCND2, CCND1, CRY1 EGLN2 2544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.