SCHEMBL23348461

SCHEMBL23348461

N#Cc1c(-n2c3ccc(-c4ccccc4)cc3c3ccc(-c4ccccc4)cc32)cc(F)cc1-n1c2ccc(-c3ccccc3)cc2c2ccc(-c3ccccc3)cc21

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.36
ADORA1 P30542 4/20 0.35
ADORA2A P29274 3/20 0.35
KDM5B Q9UGL1 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HIF1A Q16665 1/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
KDM4A O75164 1/20 0.34
SQOR Q9Y6N5 1/20 0.33
GRIA2 P42262 1/20 0.33
GRIA4 P48058 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
ADORA2B P29275 1/20 0.33
NR3C1 P04150 1/20 0.33
SERPINE1 P05121 1/20 0.32
TSPO P30536 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23348278 0.94 PGR (0.39) PGRADORA1ADORA2AKDM5BSMN1; SMN2
SCHEMBL23348236 0.93 ADORA1 (0.39) PGRADORA1ADORA2AKDM5BSMN1; SMN2
SCHEMBL23348520 0.91 KDM5B (0.36) ADORA1KDM5BSMN1; SMN2HIF1AKDM4A
SCHEMBL23348322 0.90 KIF11 (0.33) PGRADORA1ADORA2ASMN1; SMN2SQOR
SCHEMBL22155921 0.88 PGR (0.41) PGRADORA1ADORA2AKDM5BSMN1; SMN2
SCHEMBL22155922 0.88 PGR (0.39) PGRADORA1ADORA2AKDM5BCYP11B1
SCHEMBL23348456 0.88 SMN1; SMN2 (0.45) ADORA1KDM5BSMN1; SMN2HIF1AKDM4A
SCHEMBL22155913 0.88 PGR (0.39) PGRADORA1ADORA2AKDM5BSMN1; SMN2
SCHEMBL22155914 0.88 PGR (0.37) PGRADORA1ADORA2ACYP11B1CYP11B2
SCHEMBL23348308 0.87 KDM5B (0.34) PGRADORA1ADORA2AKDM5BSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210139425-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210139425-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CCND2, CCND1, CRY1 PGR 2039/4885ADORA1 2252/4885ADORA2A 2152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.