SCHEMBL23348685

SCHEMBL23348685

Fc1cc(-c2nc(-c3cnc(F)c(F)c3)nc(-c3cnc(F)c(F)c3)n2)cnc1F

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 2/20 0.36
VRK1 Q99986 2/20 0.33
BACE1 P56817 1/20 0.33
PDGFRB P09619 4/20 0.32
PDGFRA P16234 4/20 0.32
ALOX5AP P20292 2/20 0.32
FEN1 P39748 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28901470 0.88 NPC1 (0.45)
SCHEMBL30030617 0.88 NPC1 (0.45)
SCHEMBL29582214 0.76 VRK1 (0.38) GRM5VRK1BACE1PDGFRBPDGFRA
SCHEMBL2696903 0.74 VRK1 (0.40) GRM5VRK1PDGFRBPDGFRA
SCHEMBL29384015 0.69
SCHEMBL781323 0.69
SCHEMBL8774747 0.66 EGLN1 (0.42) GRM5PDGFRBPDGFRA
SCHEMBL2698622 0.66 BACE1 (0.42) GRM5BACE1ALOX5APFEN1
SCHEMBL2698140 0.66 ERN1 (0.50) ALOX5APFEN1
SCHEMBL8030847 0.65 EIF4A3 (0.33) BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230345823-A1 N-TYPE SEMICONDUCTOR, AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-10-26 US disclosed
US-20230345823-A1 N-TYPE SEMICONDUCTOR, AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-10-26 US disclosed
US-11737359-B2 N-type semiconductor, and organic photoelectric device, image sensor, and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-08-22 US disclosed
US-11737359-B2 N-type semiconductor, and organic photoelectric device, image sensor, and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-08-22 US disclosed
US-20210143338-A1 N-TYPE SEMICONDUCTOR, AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230345823-A1 N-TYPE SEMICONDUCTOR, AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING THE SAME NCS1, SCN1A, SCN1B GRM5 4652/4885VRK1 1787/4885BACE1 2625/4885
US-11737359-B2 N-type semiconductor, and organic photoelectric device, image sensor, and electronic device including the same NCS1, SCN1A, SCN1B GRM5 4652/4885VRK1 1787/4885BACE1 2625/4885
US-20210143338-A1 N-TYPE SEMICONDUCTOR, AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING THE SAME NCS1, SCN1A, SCN1B GRM5 4652/4885VRK1 1787/4885BACE1 2625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.