SCHEMBL23348686

SCHEMBL23348686

Clc1cc(-c2nc(-c3ccnc(Cl)c3)nc(-c3ccnc(Cl)c3)n2)ccn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.53
S1PR1 P21453 3/20 0.45
S1PR3 Q99500 2/20 0.45
ADORA2A P29274 1/20 0.45
ADORA1 P30542 1/20 0.45
RECQL P46063 1/20 0.43
LOX P28300 1/20 0.43
LOXL3 P58215 1/20 0.43
LOXL2 Q9Y4K0 1/20 0.43
CYP19A1 P11511 1/20 0.42
CCNC P24863 1/20 0.42
CDK8 P49336 1/20 0.42
TRPA1 O75762 1/20 0.39
MAPK13 O15264 1/20 0.39
MAPK12 P53778 1/20 0.39
MAPK11 Q15759 1/20 0.39
MAPK14 Q16539 1/20 0.39
CDC7 O00311 1/20 0.38
ROCK2 O75116 1/20 0.38
MAP4K4 O95819 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18253554 0.90 ADORA2A (0.54) IDO1S1PR1S1PR3ADORA2AADORA1
SCHEMBL18770607 0.87 ADORA2A (0.51) IDO1S1PR1S1PR3ADORA2AADORA1
SCHEMBL29701969 0.87 ADORA2A (0.51) IDO1S1PR1S1PR3ADORA2AADORA1
SCHEMBL4027001 0.85 IDO1 (0.55) IDO1S1PR1S1PR3ADORA2AADORA1
SCHEMBL31447381 0.84 IDO1 (0.52) IDO1S1PR1S1PR3ADORA2AADORA1
SCHEMBL29702043 0.81 ADORA2A (0.50) IDO1S1PR1S1PR3ADORA2AADORA1
SCHEMBL2324857 0.80 IDO1 (0.45) IDO1S1PR1S1PR3ADORA2AADORA1
SCHEMBL14488286 0.78 IDO1 (0.44) IDO1S1PR1S1PR3ADORA2AADORA1
SCHEMBL4090822 0.77 METAP1 (0.56) IDO1S1PR1S1PR3ADORA2AADORA1
SCHEMBL4672168 0.76 LMNA (0.52) IDO1S1PR1S1PR3ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230345823-A1 N-TYPE SEMICONDUCTOR, AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-10-26 US disclosed
US-20230345823-A1 N-TYPE SEMICONDUCTOR, AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-10-26 US disclosed
US-11737359-B2 N-type semiconductor, and organic photoelectric device, image sensor, and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-08-22 US disclosed
US-11737359-B2 N-type semiconductor, and organic photoelectric device, image sensor, and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-08-22 US disclosed
US-20210143338-A1 N-TYPE SEMICONDUCTOR, AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230345823-A1 N-TYPE SEMICONDUCTOR, AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING THE SAME NCS1, SCN1A, SCN1B IDO1 1534/4885S1PR1 3559/4885S1PR3 4293/4885
US-11737359-B2 N-type semiconductor, and organic photoelectric device, image sensor, and electronic device including the same NCS1, SCN1A, SCN1B IDO1 1534/4885S1PR1 3559/4885S1PR3 4293/4885
US-20210143338-A1 N-TYPE SEMICONDUCTOR, AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING THE SAME NCS1, SCN1A, SCN1B IDO1 1534/4885S1PR1 3559/4885S1PR3 4293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.