Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 5/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 2/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20059085 | 1.00 | HINT1 (0.48) | HINT1TAAR1FUT5GSK3ARPS6KA3 | |
| SCHEMBL22474866 | 0.83 | HINT1 (0.38) | HINT1NT5E | |
| SCHEMBL20841231 | 0.83 | ADORA3 (0.47) | HINT1 | |
| SCHEMBL23348935 | 0.83 | HINT1 (0.38) | HINT1NT5E | |
| SCHEMBL25713349 | 0.81 | HINT1 (0.54) | HINT1TAAR1FUT5GSK3ARPS6KA3 | |
| SCHEMBL25713720 | 0.80 | POLB (0.47) | HINT1TAAR1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL21562192 | 0.79 | HPGD (0.52) | HINT1TAAR1FUT5HPGDNT5E | |
| SCHEMBL20059041 | 0.79 | HPGD (0.52) | HINT1TAAR1FUT5HPGDNT5E | |
| SCHEMBL19242512 | 0.79 | HPGD (0.52) | HINT1TAAR1FUT5HPGDNT5E | |
| SCHEMBL19035691 | 0.79 | HPGD (0.52) | HINT1TAAR1FUT5HPGDNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852603-B1 | D-AMINO ACID COMPOUNDS FOR LIVER DISEASE | IDENIX PHARMACEUTICALS LLC (US) | 2021-05-12 | — | — | EP | disclosed |