SCHEMBL23350883

SCHEMBL23350883

CC(=O)OCc1ccc(NC(=O)C(CCCNC(N)=O)NC(=O)C(NC(=O)CCOCCOCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O)C(C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ FAP Q12884 5/20 0.42
▸ MAP1LC3B Q9GZQ8 2/20 0.38
▸ OPRK1 P41145 2/20 0.37
▸ SIRT2 Q8IXJ6 6/20 0.35
▸ SIRT1 Q96EB6 5/20 0.35
▸ SIRT5 Q9NXA8 1/20 0.34
▸ SIRT3 Q9NTG7 3/20 0.34
▸ FURIN P09958 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22910385 1.00 FAP (0.42) FAPMAP1LC3BOPRK1SIRT2SIRT1
SCHEMBL17815405 1.00 FAP (0.42) FAPMAP1LC3BOPRK1SIRT2SIRT1
SCHEMBL17722953 1.00 FAP (0.42) FAPMAP1LC3BOPRK1SIRT2SIRT1
SCHEMBL23347004 1.00 FAP (0.42) FAPMAP1LC3BOPRK1SIRT2SIRT1
SCHEMBL19046497 1.00 FAP (0.42) FAPMAP1LC3BOPRK1SIRT2SIRT1
SCHEMBL23347041 1.00 FAP (0.42) FAPMAP1LC3BOPRK1SIRT2SIRT1
SCHEMBL25094809 0.95 FAP (0.42) FAPMAP1LC3BOPRK1SIRT2SIRT1
SCHEMBL23347003 0.95 FAP (0.42) FAPMAP1LC3BOPRK1SIRT2SIRT1
SCHEMBL24648759 0.95 FAP (0.42) FAPMAP1LC3BOPRK1SIRT2SIRT1
SCHEMBL21474394 0.95 FAP (0.42) FAPMAP1LC3BOPRK1SIRT2SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210154317-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS ARS Pharmaceuticals, Inc. 2021-05-27 — — US disclosed
US-20210139604-A1 COMPOSITIONS OF ANTIBODY CONSTRUCT-AGONIST CONJUGATES AND METHODS OF USE THEREOF OPI VI - IP HOLDCO LLC 2021-05-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210139604-A1 COMPOSITIONS OF ANTIBODY CONSTRUCT-AGONIST CONJUGATES AND METHODS OF USE THEREOF STING1, CGAS, TLR7 FAP 4182/4885MAP1LC3B 3751/4885OPRK1 1035/4885
US-20210154317-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS HAVCR2, FCGR3B, FCGR1A FAP 1050/4885MAP1LC3B 1112/4885OPRK1 1836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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