Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27994057 | 0.96 | PLA2G2A (0.59) | PLA2G2AKMT2AMEN1PKMRAB9A | |
| SCHEMBL12733612 | 0.95 | PLA2G2A (0.58) | PLA2G2AKMT2AMEN1PKMRAB9A | |
| SCHEMBL29788135 | 0.95 | PLA2G2A (0.58) | PLA2G2AKMT2AMEN1PKMRAB9A | |
| SCHEMBL90428 | 0.95 | PLA2G2A (0.58) | PLA2G2AKMT2AMEN1PKMRAB9A | |
| SCHEMBL3487150 | 0.91 | PLA2G2A (0.67) | PLA2G2AKMT2AMEN1PKMRAB9A | |
| SCHEMBL5223976 | 0.90 | PLA2G2A (0.54) | PLA2G2AKMT2AMEN1PKMRAB9A | |
| SCHEMBL7598590 | 0.90 | PLA2G2A (0.53) | PLA2G2AKMT2AMEN1PKM | |
| SCHEMBL16533944 | 0.90 | PLA2G2A (0.53) | PLA2G2AKMT2AMEN1PKMRAB9A | |
| SCHEMBL30091972 | 0.88 | PLA2G2A (0.55) | PLA2G2AKMT2AMEN1PKMTP53 | |
| SCHEMBL17823602 | 0.88 | PLA2G2A (0.55) | PLA2G2AKMT2AMEN1PKMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139521-A1 | DIARYL TREHALOSE COMPOUNDS AND USES THEREOF | THE UNIV OF MONTANA (US) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139521-A1 | DIARYL TREHALOSE COMPOUNDS AND USES THEREOF | TREH, STT3B, DDOST | PLA2G2A 2835/4885KMT2A 4228/4885MEN1 3708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.