Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA3 | P07451 | 2/20 | 0.61 |
| ▸ | CA4 | P22748 | 2/20 | 0.61 |
| ▸ | CA6 | P23280 | 2/20 | 0.61 |
| ▸ | CA5A | P35218 | 2/20 | 0.61 |
| ▸ | CA7 | P43166 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3054555 | 1.00 | DNM1 (0.61) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL1948713 | 1.00 | DNM1 (0.61) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL5085490 | 1.00 | DNM1 (0.61) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL2796068 | 1.00 | DNM1 (0.61) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL2031871 | 1.00 | DNM1 (0.61) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL4755739 | 1.00 | DNM1 (0.61) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL4755756 | 1.00 | DNM1 (0.61) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL4754026 | 1.00 | DNM1 (0.61) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL2796425 | 1.00 | DNM1 (0.61) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL233652 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3401369-B1 | PROCESS FOR MAKING AN ANTI-REFLECTIVE COATING COMPOSITION AND A POROUS COATING MADE THEREFROM | COVESTRO NETHERLANDS BV (NL) | 2023-07-19 | — | — | EP | claimed |
| US-20230174509-A1 | THERAPEUTIC USE OF PLEUROMUTILINS | ARIVA MED GMBH (AT) | 2023-06-08 | — | — | US | claimed |
| US-RE49481-E1 | Compounds for the treatment and prophylaxis of respiratory syncytial virus disease | HOFFMANN-LA ROCHE INC. (US) | 2023-04-04 | — | — | US | claimed |
| EP-4135683-A1 | THERAPEUTIC USE OF PLEUROMUTILINS | Nabriva Therapeutics GMBH (AT) | 2023-02-22 | — | — | EP | claimed |
| CN-115413238-A | Therapeutic use of pleuromutilin compounds | 纳布里瓦治疗有限责任公司 | 2022-11-29 | — | — | CN | claimed |
| CN-115368824-A | Fast curing migration-free compositions based on organic polymers containing silane groups | SIKA技术股份公司 | 2022-11-22 | — | — | CN | claimed |
| WO-2021209596-A1 | THERAPEUTIC USE OF PLEUROMUTILINS | Nabriva Therapeutics GmbH (AT) | 2021-10-21 | — | — | WO | claimed |
| EP-3131994-B1 | FAST CURING MIGRATION-FREE COMPOSITION BASED ON ORGANIC POLYMERS CONTAINING SILANE GROUPS | SIKA TECH AG (CH) | 2021-06-09 | — | — | EP | claimed |
| EP-3096751-B1 | 12-EPI-PLEUROMUTILINS | Nabriva Therapeutics GmbH (AT) | 2021-01-06 | — | — | EP | claimed |
| CN-105916499-B | 12-epi-pleuromutilins | 纳布里瓦治疗股份公司 | 2020-02-18 | — | — | CN | claimed |
| WO-2013020993-A1 | COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2013-02-14 | — | — | WO | claimed |
| CN-101180275-A | Tetrahydroindolone and tetrahydroindazolone derivatives | SERENEX INC (US) | 2008-05-14 | — | — | CN | claimed |
| US-5554339-A | Process for the manufacture of wholly microfabricated biosensors | I-STAT CORPORATION (US) | 1996-09-10 | — | — | US | claimed |
| EP-0523965-B1 | Salts of N-nitrosophenylhydroxylamine | ROHM & HAAS (US) | 1996-03-06 | — | — | EP | claimed |
| US-5466575-A | Process for the manufacture of wholly microfabricated biosensors | I-STAT CORPORATION (US) | 1995-11-14 | — | — | US | claimed |
| EP-0523965-A1 | Salts of N-nitrosophenylhydroxylamine | ROHM AND HAAS COMPANY (US) | 1993-01-20 | — | — | EP | claimed |
| US-4822872-A | PREFERENTIAL ADSORPTION OF IMPURITIES ON WATER INSOLUBLE CARRIER WITH AMINE OR ALDEHYDE LIGANDS | GREEN CROSS CORPORATION (JP) | 1989-04-18 | — | — | US | claimed |
| US-4710491-A | N-glycosylated carboxylic acid derivatives as agents for combating rheumatic diseases | TROPONWERKE GMBH & CO., KG (DE) | 1987-12-01 | — | — | US | claimed |
| EP-0245875-A2 | Method of purifying factor VIII | GREEN CROSS CORPORATION (JP) | 1987-11-19 | — | — | EP | claimed |
| EP-0230242-A2 | Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-29 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174509-A1 | THERAPEUTIC USE OF PLEUROMUTILINS | MLN, PLEC, PELP1 | DNM1 4766/4885CA12 450/4885CA1 3490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.