Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23368171 | 0.80 | EGFR (0.45) | LRRK2 | |
| SCHEMBL24926748 | 0.79 | BACE1 (0.36) | LRRK2 | |
| SCHEMBL23355413 | 0.77 | LRRK2 (0.40) | LRRK2 | |
| SCHEMBL23355338 | 0.72 | KDM4E (0.38) | — | |
| SCHEMBL23355478 | 0.72 | MAPT (0.34) | — | |
| SCHEMBL23355389 | 0.70 | KDM4E (0.36) | — | |
| SCHEMBL23355470 | 0.70 | KDM4E (0.36) | — | |
| SCHEMBL23355350 | 0.69 | MAPK14 (0.35) | — | |
| SCHEMBL21612850 | 0.68 | MAPT (0.33) | — | |
| SCHEMBL23355422 | 0.68 | ADORA1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822263-A1 | BIARYL ETHER-TYPE QUINAZOLINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2021-05-19 | — | — | EP | disclosed |