Phenol

Phenol

SCHEMBL2335581

C[SiH](C)[Zr+2](C1C=Cc2ccccc21)C1C=Cc2ccccc21.[O-]c1ccccc1.[O-]c1ccccc1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.33
HTR6 P50406 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6917721 0.90 HTR6 (0.33) SIGMAR1HTR6
Hydrochloric Acid SCHEMBL6917310 0.89 HTR6 (0.32) SIGMAR1HTR6
Bromide SCHEMBL6910531 0.89 HTR2A (0.37) SIGMAR1HTR6
Fluoride Ion SCHEMBL29898462 0.89 HTR2A (0.33) SIGMAR1HTR6
Hydrochloric Acid SCHEMBL60273 0.89 HTR2A (0.33) SIGMAR1HTR6
SCHEMBL5838450 0.89 HTR2A (0.33) SIGMAR1HTR6
Iodide SCHEMBL29898384 0.89 HTR2A (0.33) SIGMAR1HTR6
Fluoride Ion SCHEMBL1130679 0.89 HTR2A (0.33) SIGMAR1HTR6
Bromide SCHEMBL29898437 0.89 HTR2A (0.37) SIGMAR1HTR6
Hydrochloric Acid SCHEMBL723185 0.89 HTR2A (0.33) SIGMAR1HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2125846-A2 PROCESS FOR PREPARING DIALKYL OXIDE METALLOCENES OR DIARYL OXIDE METALLOCENES Chemtura Organometallics GmbH (DE) 2009-12-02 EP claimed
WO-2008104382-A2 PROCESS FOR PREPARING DIALKYL OXIDE METALLOCENES OR DIARYL OXIDE METALLOCENES CHEMTURA ORGANOMETALLICS GMBH (DE) 2008-09-04 WO claimed
US-8071802-B2 Process for preparing dialkyl oxide metallocenes or diaryl oxide metallocenes CHEMTURA CORPORATION (US) 2011-12-06 US disclosed
EP-2125846-B1 PROCESS FOR PREPARING DIALKYL OXIDE METALLOCENES OR DIARYL OXIDE METALLOCENES CHEMTURA ORGANOMETALLICS GMBH (DE) 2011-08-24 EP disclosed
US-20100137624-A1 PROCESS FOR PREPARING DIALKYL OXIDE METALLOCENES OR DIARYL OXIDE METALLOCENES CHEMTURA ORGANOMETALLICS GMBH (DE) 2010-06-03 US disclosed
EP-2125846-A2 PROCESS FOR PREPARING DIALKYL OXIDE METALLOCENES OR DIARYL OXIDE METALLOCENES Chemtura Organometallics GmbH (DE) 2009-12-02 EP disclosed
WO-2008104382-A2 PROCESS FOR PREPARING DIALKYL OXIDE METALLOCENES OR DIARYL OXIDE METALLOCENES CHEMTURA ORGANOMETALLICS GMBH (DE) 2008-09-04 WO disclosed