Hydrochloric Acid

Hydrochloric Acid

SCHEMBL723185

C[SiH](C)[Zr+2]([C@@H]1C=Cc2ccccc21)[C@H]1C=Cc2ccccc21.[Cl-].[Cl-]

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.31
CHRM1 known ✓ P11229 1/20 0.31
CHRM3 known ✓ P20309 1/20 0.31
SLC6A2 known ✓ P23975 1/20 0.31
SLC6A3 known ✓ Q01959 1/20 0.31
HTR2A P28223 2/20 0.33
HTR6 P50406 1/20 0.33
SIGMAR1 Q99720 4/20 0.31
KDM4E B2RXH2 2/20 0.31
BRD4 O60885 1/20 0.31
CCL2 P13500 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
NFKB1 P19838 1/20 0.31
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL60273 1.00 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
Hydrochloric Acid SCHEMBL6909128 0.98 HTR6 (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
Bromide SCHEMBL6910231 0.98 HTR2A (0.36) HTR2AHTR6SIGMAR1KDM4EBRD4
Hydrochloric Acid SCHEMBL6917310 0.96 HTR6 (0.32) HTR2AHTR6SIGMAR1
Bromide SCHEMBL6910531 0.96 HTR2A (0.37) HTR2AHTR6SIGMAR1KDM4EBRD4
Bromide SCHEMBL29898437 0.96 HTR2A (0.37) HTR2AHTR6SIGMAR1KDM4EBRD4
Fluoride Ion SCHEMBL29898462 0.96 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
Iodide SCHEMBL29898384 0.96 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL5838450 0.96 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
Fluoride Ion SCHEMBL1130679 0.96 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8557902-B2 Functionalizable synthetic hydrocarbon fluids and integrated method for production thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-10-15 US claimed
EP-2609125-A2 FUNCTIONALIZABLE SYNTHETIC HYDROCARBON FLUIDS AND INTEGRATED METHOD OF FOR PRODUCTION THEREOF ExxonMobil Chemical Patents Inc. (US) 2013-07-03 EP claimed
US-20120053309-A1 Functionalizable Synthetic Hydrocarbon Fluids and Integrated Method for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2012-03-01 US claimed
WO-2012027139-A2 FUNCTIONALIZABLE SYNTHETIC HYDROCARBON FLUIDS AND INTEGRATED METHOD OF FOR PRODUCTION THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-03-01 WO claimed
US-5324801-A Without ring opening; aluminoxane and a steriorigid metallocene catalyst HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-28 US claimed
EP-1529067-B1 PROCESS FOR THE OLIGOMERIZATION OF A OLEFINS HAVING LOW UNSATURATION CHEMTURA CORP (US) 2017-07-05 EP disclosed
US-9469704-B2 Utilization of linear alpha olefins in the production of metallocene catalyzed poly-alpha olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-10-18 US disclosed
US-9365663-B2 Production of shear-stable high viscosity PAO EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-06-14 US disclosed
US-20140323665-A1 Polyalphaolefins by Oligomerization and Isomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-10-30 US disclosed
US-8557902-B2 Functionalizable synthetic hydrocarbon fluids and integrated method for production thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-10-15 US disclosed
EP-2640757-A2 PROCESSES FOR MAKING MULTIMODAL MOLECULAR WEIGHT DISTRIBUTION POLYOLEFINS ExxonMobil Chemical Patents Inc. (US) 2013-09-25 EP disclosed
EP-2609125-A2 FUNCTIONALIZABLE SYNTHETIC HYDROCARBON FLUIDS AND INTEGRATED METHOD OF FOR PRODUCTION THEREOF ExxonMobil Chemical Patents Inc. (US) 2013-07-03 EP disclosed
US-20090247442-A1 Production of Shear-Stable High Viscosity PAO EXXONMOBIL CHEMICAL PATENTS INC. 2009-10-01 US disclosed
US-20090221775-A1 Utilization Of Linear Alpha Olefins In The Production Of Metallocene Catalyzed Poly-Alpha Olefins EXXONMOBIL CHEMICAL PATENTS INC. 2009-09-03 US disclosed
US-7129306-B2 Process for the oligomerization of α-olefins having low unsaturation CROMPTON CORPORATION (US) 2006-10-31 US disclosed
US-20040147693-A1 Process for the oligomerization of alpha-olefins having low unsaturation CROMPTON CORPORATION, A CORPORATION OF THE STATE OF DELAWARE 2004-07-29 US disclosed
US-6706828-B2 BY CATALYSIS WITH METALLOCENE CONTAINING GROUP 4B, 5B, OR6B METAL AND COCATALYST CROMPTON CORPORATION 2004-03-16 US disclosed
US-20030232937-A1 Process for the oligomerization of alpha-olefins having low unsaturation CROMPTON CORPORATION 2003-12-18 US disclosed
US-6169052-B1 CATALYST SYSTEM COMPRISING ALUMINOXANE AND A STEREORIGID METALLOCENE COMPOUND TARGOR GMBH (DE) 2001-01-02 US disclosed
US-5324801-A Without ring opening; aluminoxane and a steriorigid metallocene catalyst HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-28 US disclosed