Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CCL2 | P13500 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL723185 | 1.00 | HTR2A (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL6909128 | 0.98 | HTR6 (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Bromide SCHEMBL6910231 | 0.98 | HTR2A (0.36) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL6917310 | 0.96 | HTR6 (0.32) | HTR2AHTR6SIGMAR1 | |
| Bromide SCHEMBL6910531 | 0.96 | HTR2A (0.37) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Bromide SCHEMBL29898437 | 0.96 | HTR2A (0.37) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Fluoride Ion SCHEMBL29898462 | 0.96 | HTR2A (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Iodide SCHEMBL29898384 | 0.96 | HTR2A (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| SCHEMBL5838450 | 0.96 | HTR2A (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Fluoride Ion SCHEMBL1130679 | 0.96 | HTR2A (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1400 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122037020-A | Supported catalyst, preparation method thereof and application thereof in olefin polymerization | 中国石油化工股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| EP-3237461-B1 | PROCESS FOR THE PREPARATION OF A POLYOLEFIN HAVING ONE OR MULTIPLE END-FUNCTIONALIZED BRANCHES | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2026-03-18 | — | — | EP | claimed |
| US-12351657-B2 | Controlling long-chain branch content with dual activator-supports | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2025-07-08 | — | — | US | claimed |
| CN-120202228-A | Method for preparing polyolefin by cascade polymerization | 浙江大学衢州研究院 | 2025-06-24 | — | — | CN | claimed |
| CN-116020416-B | Method for removing metallocene catalyst | 中国石油化工股份有限公司 | 2025-06-17 | — | — | CN | claimed |
| CN-116589614-B | Method for preparing COF-supported olefin polymerization catalyst | 浙江大学衢州研究院 | 2025-05-27 | — | — | CN | claimed |
| US-20250129487-A1 | PRODUCTION METHOD FOR AMMONIA AND PRODUCTION DEVICE | NISSAN CHEMICAL CORPORATION (JP) | 2025-04-24 | — | — | US | claimed |
| CN-116023562-B | Production process of poly alpha-olefin | 中国石油化工股份有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-116023534-B | Preparation method of poly alpha-olefin | 中国石油化工股份有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-116023532-B | Preparation method of saturated metallocene poly alpha-olefin | 中国石油化工股份有限公司 | 2025-02-11 | — | — | CN | claimed |
| US-5708090-A | Process for the preparation of a polypropylene molding composition | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-13 | — | — | US | claimed |
| EP-0798315-B1 | Process for preparing highly active, stable metallocene catalyst systems, and catalyst compositions prepared according therewith | WITCO GMBH (DE) | 1997-10-29 | — | — | EP | claimed |
| EP-0610852-B1 | Process for preparing cyclo-olefin polymers | HOECHST AG (DE) | 1997-05-07 | — | — | EP | claimed |
| US-5583192-A | POLYMERIZING A CYCLOOLEFIN AND AN OLEFIN IN THE PRESENCE OF A METALLOCENE CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-10 | — | — | US | claimed |
| WO-1996035730-A1 | AMORPHOUS OLEFIN CO/TER-POLYMERS | OPTATECH CORPORATION (FI) | 1996-11-14 | — | — | WO | claimed |
| WO-1996034002-A1 | ENHANCED SYNTHESIS OF RACEMIC METALLOCENES | ALBEMARLE CORPORATION (US) | 1996-10-31 | — | — | WO | claimed |
| US-5556997-A | Enhanced synthesis of racemic metallocenes | ALBEMARLE CORPORATION (US) | 1996-09-17 | — | — | US | claimed |
| US-5545829-A | Process for preparing cycloolefin copolymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-13 | — | — | US | claimed |
| EP-0284708-B1 | Metallocene catalyst systems for olefin polymerization having a silicon hydrocarbyl bridge. | FINA TECHNOLOGY (US) | 1996-01-31 | — | — | EP | claimed |
| US-4962262-A | 1-Olefin polymer wax, and a process for the preparation thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-09 | — | — | US | claimed |