Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2334680 | 0.81 | ESR1 (0.43) | ANPEPSMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL30789009 | 0.81 | ANPEP (0.50) | ANPEPENPEPPTGS1PTGS2MAPT | |
| SCHEMBL687298 | 0.81 | ANPEP (0.50) | ANPEPENPEPPTGS1PTGS2MAPT | |
| SCHEMBL2446964 | 0.81 | ANPEP (0.50) | ANPEPENPEPPTGS1PTGS2MAPT | |
| SCHEMBL8658142 | 0.77 | ANPEP (0.53) | ANPEPENPEPPTGS1PTGS2MAPT | |
| SCHEMBL11567553 | 0.76 | ESR1 (0.41) | MAPTSMN1; SMN2ALDH1A1LMNACYP3A4 | |
| SCHEMBL2337192 | 0.75 | ANPEP (0.51) | ANPEPENPEPPTGS1PTGS2MAPT | |
| SCHEMBL7503915 | 0.75 | ANPEP (0.58) | ANPEPENPEPPTGS1PTGS2MAPT | |
| SCHEMBL371525 | 0.75 | ANPEP (0.58) | ANPEPENPEPPTGS1PTGS2MAPT | |
| SCHEMBL30444032 | 0.75 | RXRA (0.66) | ANPEPENPEPPTGS1PTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358689-A1 | Benzothiazole derivatives as anticancer agents | Takeda Pharmaceutical Company Limited (JP) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010064722-A1 | BENZOTHIAZOLE DERIVATIVES AS ANTICANCER AGENTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-10 | — | — | WO | disclosed |