Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.85 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.85 |
| ▸ | MAPT | P10636 | 3/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.85 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.85 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.85 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.85 |
| ▸ | LMNA | P02545 | 1/20 | 0.85 |
| ▸ | HPGD | P15428 | 1/20 | 0.85 |
| ▸ | TSHR | P16473 | 1/20 | 0.85 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.85 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.85 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.85 |
| ▸ | CES2 | O00748 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | EBP | Q15125 | 4/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613998 | 1.00 | ESR1 (0.85) | ESR1ADORA3MAPTKDM4EADRA1A | |
| SCHEMBL23358692 | 1.00 | ESR1 (0.85) | ESR1ADORA3MAPTKDM4EADRA1A | |
| Chlorotrianisene SCHEMBL8225 | 0.92 | HPGD (1.00) | ESR1ADORA3MAPTKDM4EADRA1A | |
| Chlorotrianisene SCHEMBL7349593 | 0.92 | HPGD (1.00) | ESR1ADORA3MAPTKDM4EADRA1A | |
| Chlorotrianisene SCHEMBL4928327 | 0.87 | MAPT (0.81) | ESR1ADORA3MAPTKDM4EADRA1A | |
| SCHEMBL68051 | 0.86 | CES2 (0.69) | ESR1ADORA3MAPTKDM4EADRA1A | |
| SCHEMBL30741457 | 0.86 | CES2 (0.69) | ESR1ADORA3MAPTKDM4EADRA1A | |
| SCHEMBL9723456 | 0.86 | CES2 (0.69) | ESR1ADORA3MAPTKDM4EADRA1A | |
| SCHEMBL68050 | 0.86 | CES2 (0.69) | ESR1ADORA3MAPTKDM4EADRA1A | |
| SCHEMBL18294893 | 0.81 | ESR1 (0.50) | ESR1ADORA3MAPTKDM4EADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11046638-B2 | Processes for the preparation of zuclomiphene and intermediates thereof | APOTEX INC. (CA) | 2021-06-29 | — | — | US | disclosed |
| US-20210147337-A1 | Processes for the Preparation of Zuclomiphene and Intermediates Thereof | THE BANK OF NOVA SCOTIA (CA) | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11046638-B2 | Processes for the preparation of zuclomiphene and intermediates thereof | CYP3A43, UGT1A3, ZDHHC7 | ESR1 2532/4885ADORA3 2676/4885MAPT 4485/4885 |
| US-20210147337-A1 | Processes for the Preparation of Zuclomiphene and Intermediates Thereof | CYP3A43, UGT1A3, ZDHHC7 | ESR1 2532/4885ADORA3 2676/4885MAPT 4485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.