SCHEMBL2335907

SCHEMBL2335907

CCOCC(=O)OOOC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
HPGD P15428 2/20 0.33
ALDH1A1 P00352 5/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9011776 0.88 TSHR (0.34) TSHRHPGDALDH1A1HSD17B10TDP1
SCHEMBL8038175 0.81 TSHR (0.38) TSHRALDH1A1HSD17B10TDP1
SCHEMBL2340678 0.79 ALDH1A1 (0.34) TSHRALDH1A1HSD17B10TDP1
SCHEMBL544189 0.79 ALDH1A1 (0.34) TSHRALDH1A1HSD17B10TDP1
SCHEMBL11852347 0.79 ALDH1A1 (0.36) TSHRALDH1A1HSD17B10TDP1
SCHEMBL28556120 0.78 MGAM (0.39) TSHRHPGDALDH1A1HSD17B10
SCHEMBL8032017 0.76 TSHR (0.38) TSHRALDH1A1HSD17B10TDP1
SCHEMBL1537758 0.75 ALDH1A1 (0.46) TSHRALDH1A1HSD17B10TDP1
SCHEMBL5607205 0.74 ALDH1A1 (0.33) TSHRHPGDALDH1A1HSD17B10
Butane SCHEMBL17512943 0.73 ALDH1A1 (0.44) TSHRALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1456257-B2 ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION AKZO NOBEL CHEMICALS INT BV (NL) 2020-04-01 EP disclosed
EP-1636272-B2 POLYMERIZATION PROCESS INVOLVING THE DOSING INITIATORS AKZO NOBEL NV (NL) 2011-08-17 EP disclosed
US-7834110-B2 Polymerization in presence of promoters and surfactant; overall polymerization time is reduced by a reduction of the pressure drop time AKZO NOBEL N. V. (NL) 2010-11-16 US disclosed
EP-1456257-B1 ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION AKZO NOBEL NV (NL) 2009-06-24 EP disclosed
US-20080221266-A1 Polymerization in presence of promoters and surfactant; overall polymerization time is reduced by a reduction of the pressure drop time AKZO NOBEL N.V. (NL) 2008-09-11 US disclosed
EP-1636272-B1 POLYMERIZATION PROCESS INVOLVING THE DOSING INITIATORS AKZO NOBEL NV (NL) 2007-12-05 EP disclosed
US-7173095-B2 Polymerization process involving the dosing initiators AKZO NOBEL N. V. (NL) 2007-02-06 US disclosed
US-7109275-B2 Co-metering of organic initiators and protective colloids during polymerization reactions AKZO NOBEL N.V. (NL) 2006-09-19 US disclosed
EP-1495057-B1 CO-METERING OF ORGANIC INITIATORS AND PROTECTIVE COLLOIDS DURING POLYMERIZATION REACTIONS AKZO NOBEL NV (NL) 2006-08-02 EP disclosed
US-20060122339-A1 Polymerization process involving the dosing initiators AKZO NOBEL N.V. (NL) 2006-06-08 US disclosed
EP-1636272-A1 POLYMERIZATION PROCESS INVOLVING THE DOSING INITIATORS Akzo Nobel N.V. (NL) 2006-03-22 EP disclosed
US-20050080207-A1 Addition of organic initiators during the pressure drop In vinyl chloride monomer polymerization reactions AKZO NOBEL N.V. (NL) 2005-04-14 US disclosed
EP-1495057-A1 CO-METERING OF ORGANIC INITIATORS AND PROTECTIVE COLLOIDS DURING POLYMERIZATION REACTIONS Akzo Nobel N.V. (NL) 2005-01-12 EP disclosed
WO-2004113392-A1 POLYMERIZATION PROCESS INVOLVING THE DOSING INITIATORS AKZO NOBEL N.V. (NL) 2004-12-29 WO disclosed
EP-1456257-A1 ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION Akzo Nobel N.V. (NL) 2004-09-15 EP disclosed
EP-1375529-A1 Addition of organic initiators during a pressure drop in vinyl chloride monomer polymerization reactions Akzo Nobel N.V. (NL) 2004-01-02 EP disclosed
WO-2003087168-A1 CO-METERING OF ORGANIC INITIATORS AND PROTECTIVE COLLOIDS DURING POLYMERIZATION REACTIONS AKZO NOBEL N.V. (NL) 2003-10-23 WO disclosed
US-20030199656-A1 Co-metering of organic initiators and protective colloids during polymerization reactions WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) 2003-10-23 US disclosed
WO-2003054039-A1 ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION REACTIONS AKZO NOBEL N.V. (NL) 2003-07-03 WO disclosed