Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27440959 | 0.94 | ALDH1A1 (0.39) | ALDH1A1CYP2C9CYP2C19APLNRKDM4E | |
| SCHEMBL3800969 | 0.89 | ALDH1A1 (0.43) | ALDH1A1TSHRDGAT1MGAMGAA | |
| Piperazine SCHEMBL27939377 | 0.88 | KDM4E (0.33) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL6688426 | 0.87 | DGAT1 (0.37) | DGAT1GAACYP2D6HDAC1HDAC2 | |
| SCHEMBL21348710 | 0.87 | ALDH1A1 (0.42) | ALDH1A1TSHRCYP2D6APLNRKDM4E | |
| SCHEMBL20547939 | 0.84 | CES2 (0.44) | ALDH1A1TSHRHDAC1HDAC2HDAC6 | |
| SCHEMBL13323676 | 0.83 | DGAT1 (0.34) | DGAT1GAACYP2D6HDAC1HDAC2 | |
| SCHEMBL13907508 | 0.83 | APLNR (0.36) | ALDH1A1DGAT1CYP2D6HDAC1HDAC2 | |
| SCHEMBL12501262 | 0.82 | ALDH1A1 (0.33) | ALDH1A1TSHRMGAMGAASI | |
| SCHEMBL5607084 | 0.82 | CES2 (0.37) | ALDH1A1DGAT1CYP2D6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699106-A | Novel trifluoromethyl propanamide derivative as HTRA1 inhibitor | 豪夫迈·罗氏有限公司 | 2018-10-23 | — | — | CN | claimed |
| CN-117715904-A | CDK2 degrading agents and uses thereof | 凯麦拉医疗公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117551089-A | Estrogen receptor proteolytic modulators and related methods of use | 阿尔维纳斯运营股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-110612297-B | Estrogen receptor proteolytic modulators and related methods of use | 阿尔维纳斯运营股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| US-20230149550-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
| CN-107567443-B | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2023-04-28 | — | — | CN | disclosed |
| CN-115925679-A | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2023-04-07 | — | — | CN | disclosed |
| CN-110143961-A | A kind of pyrrolopyridine ketone bifunctional molecule compound based on the induction BET degradation of VHL ligand | 江苏省中医药研究院 | 2019-08-20 | — | — | CN | disclosed |
| CN-108699106-A | Novel trifluoromethyl propanamide derivative as HTRA1 inhibitor | 豪夫迈·罗氏有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-103324049-B | Toner, developer, toner cartridge, developer box, handle box, image forming apparatus and image forming method | 富士施乐株式会社 | 2018-05-25 | — | — | CN | disclosed |
| CN-1166703-C | Ethylene/alpha-alefin copolymer, composition thereof, film thereof and uses of these | 日本聚烯烃株式会社 | 2004-09-15 | — | — | CN | disclosed |
| CN-1149193-C | Substituted tricyclic compound | — | 2004-05-12 | — | — | CN | disclosed |
| CN-1075062-C | Acetic acid derivatives | HOFFMANN LA ROCHE (CH) | 2001-11-21 | — | — | CN | disclosed |
| CN-1305502-A | Ethylene/alpha-alefin copolymer, composition thereof, film thereof and uses of these | JAPAN POLYOLEFINS CO LTD (JP) | 2001-07-25 | — | — | CN | disclosed |
| CN-1058706-C | Prostaglandin E, ester liposome formulations containing them and medicine containing them | ONO PHARMACETICAL CO LTD (JP) | 2000-11-22 | — | — | CN | disclosed |
| CN-1253948-A | Substituted tricyclic compound | LILLY CO ELI (US) | 2000-05-24 | — | — | CN | disclosed |
| CN-1048490-C | Cyclic derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | THOMAE GMBH DR K (DE) | 2000-01-19 | — | — | CN | disclosed |
| CN-1151398-A | Prostaglandin E, ester liposome formulations containing them and medicine containing them | ONO PHARMACEUTICAL CO (JP) | 1997-06-11 | — | — | CN | disclosed |
| CN-1112104-A | Acetic acid derivatives | HOFFMANN LA ROCHE (CH) | 1995-11-22 | — | — | CN | disclosed |
| CN-1099755-A | Cyclic derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | THOMAE GMBH DR K (DE) | 1995-03-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230149550-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | DMPK, DTYMK, MYCBP | ALDH1A1 4368/4885TSHR 2145/4885DGAT1 2859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.