Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2027985 | 0.91 | EGLN1 (0.42) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL8031597 | 0.91 | TSHR (0.42) | TSHRTDP1ALDH1A1HSD17B10 | |
| SCHEMBL1845580 | 0.91 | TSHR (0.37) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL491916 | 0.89 | DGKA (0.38) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL679714 | 0.89 | DGKA (0.38) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL1537758 | 0.89 | ALDH1A1 (0.46) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL7787918 | 0.89 | ALDH1A1 (0.34) | TSHRTDP1ALDH1A1HSD17B10 | |
| Butane SCHEMBL17512943 | 0.87 | ALDH1A1 (0.44) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL442266 | 0.87 | ALDH1A1 (0.33) | TSHRTDP1ALDH1A1HSD17B10 | |
| SCHEMBL8038175 | 0.85 | TSHR (0.38) | TSHRTDP1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000068192-A2 | PROCESS FOR THE PREPARATION OF (DI)ALKYLPEROXY ESTERS OF (DI)CARBOXYLIC ACIDS | AKZO NOBEL N.V. (NL) | 2000-11-16 | — | — | WO | disclosed |