Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829135 | 0.90 | SMN1; SMN2 (0.66) | MAPTNPSR1SMN1; SMN2POLBTDP1 | |
| SCHEMBL4006702 | 0.88 | SMN1; SMN2 (0.74) | MAPTSMN1; SMN2POLBTDP1KDM4E | |
| SCHEMBL30028627 | 0.87 | MAPT (0.68) | MAPTNPSR1SMN1; SMN2POLBTDP1 | |
| SCHEMBL7234307 | 0.85 | MAPT (0.56) | MAPTNPSR1SMN1; SMN2POLBTDP1 | |
| SCHEMBL6258641 | 0.83 | MAPT (0.64) | MAPTNPSR1POLBRAB9AGAA | |
| SCHEMBL8511661 | 0.80 | KMT2A (0.60) | MAPTSMN1; SMN2POLBKDM4EMAPK1 | |
| SCHEMBL6188814 | 0.79 | MAPT (0.52) | MAPTNPSR1SMN1; SMN2POLBTDP1 | |
| SCHEMBL6348254 | 0.77 | ENPP3 (0.62) | MAPTSMN1; SMN2TDP1KDM4EMAPK1 | |
| SCHEMBL7231587 | 0.77 | SMN1; SMN2 (0.54) | MAPTSMN1; SMN2POLBTDP1MAPK1 | |
| SCHEMBL18718147 | 0.77 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2POLBTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534155-B1 | COMPOUNDS FOR TREATING RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | BIOTA SCIENT MANAGEMENT PTY LTD (AU) | 2018-04-11 | — | — | EP | disclosed |
| US-9540387-B2 | Substituted imidazo[1,2-d]pyrrolo[1,2-d]pyrazines for treating respiratory syncytial virus infections | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2017-01-10 | — | — | US | disclosed |
| US-20160046642-A1 | Compounds for Treating Respiratory Syncytial Virus Infections | BIOTA SCIENT MANAGEMENT (AU) | 2016-02-18 | — | — | US | disclosed |
| US-9163029-B2 | Substituted imidazo[1,2-a]pyrrolo[1,2-d]pyrazines for treating respiratory syncytial virus infections | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2015-10-20 | — | — | US | disclosed |
| US-20140051697-A1 | COMPOUNDS FOR TREATING RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2014-02-20 | — | — | US | disclosed |
| US-8604034-B2 | Substituted imidazo[1,2-α]pyrrolo[1,2-d]pyrazines for treating respiratory syncytial virus (RSV) infections | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2013-12-10 | — | — | US | disclosed |
| EP-2534155-A1 | COMPOUNDS FOR TREATING RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | Biota Scientific Management Pty Ltd (AU) | 2012-12-19 | — | — | EP | disclosed |
| US-20110207728-A1 | COMPOUNDS FOR TREATING RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2011-08-25 | — | — | US | disclosed |
| WO-2011094823-A1 | COMPOUNDS FOR TREATING RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-08-11 | — | — | WO | disclosed |
| EP-1066257-A2 | HETEROCYLIC CLASSES OF COMPOUNDS FOR THE MODULATING TYROSINE PROTEIN KINASE | Sugen, Inc. (US) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999048868-A9 | HETEROCYCLIC CLASSES OF COMPOUNDS FOR THE MODULATING TYROSINE PROTEIN KINASE | SUGEN INC (US) | 2000-04-20 | — | — | WO | disclosed |
| WO-1999048868-A2 | HETEROCYCLIC CLASSES OF COMPOUNDS FOR THE MODULATING TYROSINE PROTEIN KINASE | SUGEN, INC. (US) | 1999-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207728-A1 | COMPOUNDS FOR TREATING RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | FURIN, SQOR, SUCNR1 | MAPT 4436/4885NPSR1 1458/4885SMN1; SMN2 497/4885 |
| US-20160046642-A1 | Compounds for Treating Respiratory Syncytial Virus Infections | FURIN, SQOR, SUCNR1 | MAPT 4436/4885NPSR1 1458/4885SMN1; SMN2 497/4885 |
| US-20140051697-A1 | COMPOUNDS FOR TREATING RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | FURIN, SQOR, SUCNR1 | MAPT 4436/4885NPSR1 1458/4885SMN1; SMN2 497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.