SCHEMBL23360355

SCHEMBL23360355

CC(C)(C)OC(=O)N1CCC(Nc2cccc3ncc(Cl)cc23)CC1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 3/20 0.58
ALDH1A1 P00352 2/20 0.49
NPC1 O15118 1/20 0.49
MAPT P10636 1/20 0.49
MAPK1 P28482 1/20 0.49
HTT P42858 1/20 0.49
RAB9A P51151 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
CCNT1 O60563 1/20 0.47
BRD4 O60885 1/20 0.47
STS P08842 2/20 0.46
CNR2 P34972 1/20 0.46
PIK3CA P42336 1/20 0.46
NSD2 O96028 1/20 0.45
EHMT2 Q96KQ7 1/20 0.45
DYRK1A Q13627 1/20 0.45
GPR119 Q8TDV5 1/20 0.45
NR3C1 P04150 1/20 0.45
JAK1 P23458 1/20 0.45
FNTA P49354 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29862902 0.94 CNR1 (0.52) CNR1ALDH1A1NPC1MAPTMAPK1
SCHEMBL28834015 0.94 CNR1 (0.52) CNR1ALDH1A1NPC1MAPTMAPK1
SCHEMBL29862780 0.94 CNR1 (0.52) CNR1ALDH1A1NPC1MAPTMAPK1
SCHEMBL28834016 0.94 CNR1 (0.52) CNR1ALDH1A1NPC1MAPTMAPK1
SCHEMBL28834105 0.94 CNR1 (0.52) CNR1ALDH1A1NPC1MAPTMAPK1
SCHEMBL23360335 0.88 CNR1 (0.51) CNR1ALDH1A1NPC1MAPTMAPK1
SCHEMBL23360493 0.87 ALDH1A1 (0.57) CNR1ALDH1A1NPC1MAPTMAPK1
SCHEMBL23360378 0.87 CNR1 (0.54) CNR1ALDH1A1NPC1MAPTMAPK1
SCHEMBL23360676 0.85 CNR1 (0.61) CNR1ALDH1A1NPC1MAPTMAPK1
SCHEMBL29863184 0.85 CNR1 (0.61) CNR1ALDH1A1NPC1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4055014-B1 PYRROLIDINE AND PIPERIDINE COMPOUNDS YUHAN CORP (KR) 2025-04-30 EP disclosed
CN-114867719-B Pyrrolidine and piperidine compounds 柳韩洋行 2024-06-25 CN disclosed
US-11655235-B2 Pyrrolidine and piperidine compounds YUHAN CORPORATION (KR) 2023-05-23 US disclosed
EP-4055014-A1 PYRROLIDINE AND PIPERIDINE COMPOUNDS Yuhan Corporation (KR) 2022-09-14 EP disclosed
CN-114867719-A Pyrrolidine and piperidine compounds 柳韩洋行 2022-08-05 CN disclosed
US-20210147386-A1 PYRROLIDINE AND PIPERIDINE COMPOUNDS YUHAN CORPORATION (KR) 2021-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11655235-B2 Pyrrolidine and piperidine compounds FAP, APC, VHL CNR1 3970/4885ALDH1A1 439/4885NPC1 2057/4885
US-20210147386-A1 PYRROLIDINE AND PIPERIDINE COMPOUNDS FAP, APC, VHL CNR1 3970/4885ALDH1A1 439/4885NPC1 2057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.