SCHEMBL23360515

SCHEMBL23360515

CN(c1ccc2cccnc2c1)C1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 12/20 0.48
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
POLB P06746 2/20 0.44
USP30 Q70CQ3 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29862993 1.00 GPR119 (0.48) GPR119MEN1KMT2APOLBUSP30
SCHEMBL28834113 0.94 USP30 (0.48) GPR119MEN1KMT2APOLBUSP30
SCHEMBL28833981 0.94 USP30 (0.48) GPR119MEN1KMT2APOLBUSP30
SCHEMBL28833979 0.94 USP30 (0.48) GPR119MEN1KMT2APOLBUSP30
SCHEMBL23360552 0.93 GPR119 (0.49) GPR119MEN1KMT2APOLBUSP30
SCHEMBL29862519 0.87 USP30 (0.48) GPR119MEN1KMT2APOLBUSP30
SCHEMBL28951922 0.87 USP30 (0.48) GPR119MEN1KMT2APOLBUSP30
SCHEMBL28834153 0.87 USP30 (0.48) GPR119MEN1KMT2APOLBUSP30
SCHEMBL28834154 0.87 USP30 (0.48) GPR119MEN1KMT2APOLBUSP30
SCHEMBL29862618 0.87 USP30 (0.48) GPR119MEN1KMT2APOLBUSP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4055014-B1 PYRROLIDINE AND PIPERIDINE COMPOUNDS YUHAN CORP (KR) 2025-04-30 EP disclosed
US-11655235-B2 Pyrrolidine and piperidine compounds YUHAN CORPORATION (KR) 2023-05-23 US disclosed
EP-4055014-A1 PYRROLIDINE AND PIPERIDINE COMPOUNDS Yuhan Corporation (KR) 2022-09-14 EP disclosed
CN-114867719-A Pyrrolidine and piperidine compounds 柳韩洋行 2022-08-05 CN disclosed
US-20210147386-A1 PYRROLIDINE AND PIPERIDINE COMPOUNDS YUHAN CORPORATION (KR) 2021-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11655235-B2 Pyrrolidine and piperidine compounds FAP, APC, VHL GPR119 1940/4885MEN1 2004/4885KMT2A 2822/4885
US-20210147386-A1 PYRROLIDINE AND PIPERIDINE COMPOUNDS FAP, APC, VHL GPR119 1940/4885MEN1 2004/4885KMT2A 2822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.