Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KMT5B | Q4FZB7 | 2/20 | 0.49 |
| ▸ | KMT5C | Q86Y97 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 4/20 | 0.48 |
| ▸ | TDO2 | P48775 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23360548 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1KMT2AKMT5B | |
| SCHEMBL23360560 | 0.87 | GFER (0.48) | IDO1TDO2CCNCCDK8CYP2C8 | |
| SCHEMBL23360562 | 0.87 | GFER (0.48) | IDO1TDO2CCNCCDK8CYP2C8 | |
| SCHEMBL23360245 | 0.87 | KMT2A (0.52) | ALDH1A1KDM4EMEN1KMT2AKMT5B | |
| SCHEMBL23360247 | 0.87 | KMT2A (0.52) | ALDH1A1KDM4EMEN1KMT2AKMT5B | |
| SCHEMBL28833982 | 0.85 | CNR1 (0.55) | ALDH1A1KDM4EMEN1KMT2AIDO1 | |
| SCHEMBL29933511 | 0.85 | CNR1 (0.55) | ALDH1A1KDM4EMEN1KMT2AIDO1 | |
| SCHEMBL23360554 | 0.84 | MCHR1 (0.53) | KDM4ECYP2D6NOS1NOS2MAPK1 | |
| SCHEMBL23360083 | 0.84 | HDAC8 (0.45) | ALDH1A1KDM4EMEN1KMT2AIDO1 | |
| SCHEMBL23360081 | 0.84 | HDAC8 (0.45) | ALDH1A1KDM4EMEN1KMT2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655235-B2 | Pyrrolidine and piperidine compounds | YUHAN CORPORATION (KR) | 2023-05-23 | — | — | US | disclosed |
| EP-4055014-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | Yuhan Corporation (KR) | 2022-09-14 | — | — | EP | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |
| US-20210147386-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | YUHAN CORPORATION (KR) | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655235-B2 | Pyrrolidine and piperidine compounds | FAP, APC, VHL | ALDH1A1 439/4885KDM4E 1644/4885MEN1 2004/4885 |
| US-20210147386-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | FAP, APC, VHL | ALDH1A1 439/4885KDM4E 1644/4885MEN1 2004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.