Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 7/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CCNH | P51946 | 1/20 | 0.40 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23360110 | 1.00 | MTNR1B (0.46) | MTNR1BMTNR1APIK3CDNOS3NOS1 | |
| SCHEMBL23360112 | 1.00 | MTNR1B (0.46) | MTNR1BMTNR1APIK3CDNOS3NOS1 | |
| SCHEMBL28834217 | 0.88 | PIK3CD (0.54) | MTNR1BMTNR1APIK3CDEGFRPIK3CA | |
| SCHEMBL28834216 | 0.88 | PIK3CD (0.54) | MTNR1BMTNR1APIK3CDEGFRPIK3CA | |
| SCHEMBL29933521 | 0.88 | PIK3CD (0.54) | MTNR1BMTNR1APIK3CDEGFRPIK3CA | |
| SCHEMBL29863056 | 0.88 | PIK3CD (0.54) | MTNR1BMTNR1APIK3CDEGFRPIK3CA | |
| SCHEMBL23360581 | 0.86 | PIK3CD (0.40) | PIK3CDPIK3CAPIK3CBPIK3CGROCK2 | |
| SCHEMBL23360582 | 0.86 | PIK3CD (0.40) | PIK3CDPIK3CAPIK3CBPIK3CGROCK2 | |
| SCHEMBL23360554 | 0.84 | MCHR1 (0.53) | MTNR1BNOS3NOS1NOS2CCNA2 | |
| SCHEMBL23360667 | 0.84 | CCNK (0.44) | EGFRROCK2CCNA2CDK2CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655235-B2 | Pyrrolidine and piperidine compounds | YUHAN CORPORATION (KR) | 2023-05-23 | — | — | US | disclosed |
| EP-4055014-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | Yuhan Corporation (KR) | 2022-09-14 | — | — | EP | disclosed |
| US-20210147386-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | YUHAN CORPORATION (KR) | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655235-B2 | Pyrrolidine and piperidine compounds | FAP, APC, VHL | MTNR1B 4021/4885MTNR1A 4529/4885PIK3CD 641/4885 |
| US-20210147386-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | FAP, APC, VHL | MTNR1B 4021/4885MTNR1A 4529/4885PIK3CD 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.