SCHEMBL23360770

SCHEMBL23360770

C[C@@H]([Si](C)(C)C)S(N)(=O)=O

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
APLNR P35414 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131596 1.00 CA1 (0.41) CA1CA2CA9APLNR
SCHEMBL1115357 0.69
SCHEMBL2864770 0.69
SCHEMBL43258 0.68
SCHEMBL1785369 0.67 MEN1 (0.30)
SCHEMBL8083316 0.65
Bromide SCHEMBL30609919 0.65
SCHEMBL2129023 0.65
SCHEMBL9710368 0.65 CA2 (0.44) CA1CA2CA9APLNR
Iodide SCHEMBL28619013 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240158466-A1 PEGYLATED P-SELECTIN INHIBITORS BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 2024-05-16 US disclosed
US-20210147598-A1 FUNCTIONAL OLIGOMERS AND FUNCTIONAL POLYMERS INCLUDING HYDROXYLATED POLYMERS AND CONJUGATES THEREOF AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2021-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147598-A1 FUNCTIONAL OLIGOMERS AND FUNCTIONAL POLYMERS INCLUDING HYDROXYLATED POLYMERS AND CONJUGATES THEREOF AND USES THEREOF PUF60, PGLS, PARG CA1 2704/4885CA2 4147/4885CA9 2925/4885
US-20240158466-A1 PEGYLATED P-SELECTIN INHIBITORS SELP, SELE, SELPLG CA1 3038/4885CA2 4572/4885CA9 2924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.