Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.40 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | KCNK13 | Q9HB14 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23361958 | 0.91 | ALDH1A1 (0.50) | CSF1RHTTALDH1A1POLBGRIN1 | |
| SCHEMBL23361862 | 0.87 | CSF1R (0.57) | CSF1RHTTALDH1A1POLBKMT2A | |
| SCHEMBL23361807 | 0.87 | POLB (0.57) | CSF1RHTTALDH1A1POLBGRIN2B | |
| SCHEMBL23361964 | 0.80 | POLB (0.69) | CSF1RHTTALDH1A1POLBGRIN2B | |
| SCHEMBL990644 | 0.74 | HTT (0.66) | CSF1RHTTALDH1A1POLBKMT2A | |
| SCHEMBL17487443 | 0.74 | TYMS (0.47) | CSF1RHTTALDH1A1POLBGRIN1 | |
| SCHEMBL4083456 | 0.73 | PPARG (0.47) | HTTPOLBKMT2ATSHR | |
| SCHEMBL23361809 | 0.71 | CSF1R (0.76) | CSF1RHTTALDH1A1POLBKMT2A | |
| SCHEMBL22726431 | 0.69 | MCHR1 (0.55) | ALDH1A1POLBTSHR | |
| SCHEMBL20715421 | 0.69 | HTR3A (0.53) | SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021096314-A1 | NOVEL BENZIMIDAZOLE DERIVATIVE AND USE THEREOF | 가천대학교 산학협력단 | 2021-05-20 | — | — | WO | disclosed |