Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | TNF | P01375 | 2/20 | 0.61 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.61 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.61 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.61 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.61 |
| ▸ | CSF1R | P07333 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7168102 | 0.90 | KMT2A (0.71) | HTTKMT2ATNFNOD2NOD1 | |
| SCHEMBL23361962 | 0.85 | KMT2A (0.66) | HTTKMT2ATNFNOD2NOD1 | |
| SCHEMBL16512786 | 0.84 | KMT2A (0.64) | HTTKMT2ATNFNOD2NOD1 | |
| SCHEMBL9630558 | 0.84 | TNF (0.75) | HTTTSHRKMT2ATNFNOD2 | |
| SCHEMBL939417 | 0.83 | TNF (0.79) | HTTTSHRKMT2ATNFNOD2 | |
| SCHEMBL31633144 | 0.83 | TSHR (0.66) | HTTTSHRKMT2ATNFMEN1 | |
| SCHEMBL23361856 | 0.83 | MAPT (0.69) | HTTTSHRKMT2ATNFNOD2 | |
| Hydrochloric Acid SCHEMBL11594488 | 0.82 | TNF (0.73) | HTTTSHRKMT2ATNFNOD2 | |
| Fluoride SCHEMBL10353244 | 0.82 | HTT (0.62) | HTTTSHRKMT2AMEN1ALOX5AP | |
| SCHEMBL7165480 | 0.81 | TNF (0.87) | HTTKMT2ATNFNOD2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200377505-A1 | BENZIMIDAZOLES AND AZA-BENZIMIDAZOLES, AND METHODS OF USE THEREOF | GFB (ABC), LLC | 2020-12-03 | — | — | US | disclosed |
| WO-2019028308-A1 | BENZIMIDAZOLES AND AZA-BENZIMIDAZOLES, AND METHODS OF USE THEREOF | GOLDFINCH BIO, INC. (US) | 2019-02-07 | — | — | WO | disclosed |
| US-7863310-B2 | Kinase inhibitors | ELI LILLY AND COMPANY (US) | 2011-01-04 | — | — | US | disclosed |
| US-20080227839-A1 | Kinase Inhibitors | ELI LILLY AND COMPANY | 2008-09-18 | — | — | US | disclosed |
| EP-0145037-B1 | N-(BICYCLIC HETEROCYCLYL)-4-PIPERIDINAMINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-01-18 | — | — | EP | disclosed |
| US-4634704-A | HISTAMINE AND SEROTONINE ANTAGONISTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 1987-01-06 | — | — | US | disclosed |
| EP-0145037-A2 | N-(bicyclic heterocyclyl)-4-piperidinamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1985-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200377505-A1 | BENZIMIDAZOLES AND AZA-BENZIMIDAZOLES, AND METHODS OF USE THEREOF | AZI2, ATP6V1B1, GLS | HTT 3957/4885TSHR 3340/4885KMT2A 1233/4885 |
| US-20080227839-A1 | Kinase Inhibitors | ABL1, MAP3K20, MAP3K19 | HTT 4547/4885TSHR 2811/4885KMT2A 1066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.