Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RORB | Q92753 | 3/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12443300 | 0.81 | CNR2 (0.45) | TSHRALDH1A1L3MBTL1TNKSPARP1 | |
| SCHEMBL15143986 | 0.80 | TSHR (0.40) | TSHRPKMALDH1A1L3MBTL1CYP2C9 | |
| SCHEMBL5672240 | 0.74 | TSHR (0.40) | TSHRPKMALDH1A1L3MBTL1CYP2C9 | |
| SCHEMBL5675082 | 0.73 | ALDH1A1 (0.42) | TSHRPKMALDH1A1L3MBTL1CYP2C9 | |
| SCHEMBL15143983 | 0.73 | PARP15 (0.43) | ALDH1A1TNKSPARP1PARP15TNKS2 | |
| SCHEMBL15143985 | 0.72 | TSHR (0.38) | TSHRPKMALDH1A1L3MBTL1CYP2C9 | |
| SCHEMBL5675093 | 0.72 | TSHR (0.41) | TSHRPKMALDH1A1L3MBTL1CYP2C9 | |
| SCHEMBL10717481 | 0.72 | TSHR (0.56) | TSHRPKMALDH1A1CYP2C9P2RX7 | |
| SCHEMBL15143958 | 0.71 | CNR2 (0.46) | TSHRPKMALDH1A1CYP2C9P2RX7 | |
| SCHEMBL15143977 | 0.69 | CNR2 (0.54) | TSHRALDH1A1CYP1A2CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130196960-A1 | Cannabinoid Receptor Agonists | IRONWOOD PHARMACEUTICALS, INC. (US) | 2013-08-01 | — | — | US | disclosed |
| US-20130196960-A1 | Cannabinoid Receptor Agonists | IRONWOOD PHARMACEUTICALS, INC. (US) | 2013-08-01 | — | — | US | disclosed |
| US-20130196960-A1 | Cannabinoid Receptor Agonists | IRONWOOD PHARMACEUTICALS, INC. (US) | 2013-08-01 | — | — | US | disclosed |
| WO-2011100324-A1 | CANNABINOID RECEPTOR AGONISTS | Ironwood Pharmaceuticals Inc. (US) | 2011-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130196960-A1 | Cannabinoid Receptor Agonists | CNR2, CNR1, GPR18 | TSHR 460/4885PKM 3699/4885ALDH1A1 2610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.