Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | LTA4H | P09960 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5568576 | 0.86 | LTA4H (0.65) | SIGMAR1LTA4HHRH3USP2ALDH1A1 | |
| SCHEMBL19234679 | 0.86 | SIGMAR1 (0.73) | SIGMAR1KDM4ERECQLTDP1HRH3 | |
| SCHEMBL1730306 | 0.85 | LTA4H (0.77) | SIGMAR1LTA4HHRH3USP2ALDH1A1 | |
| SCHEMBL3866360 | 0.84 | SIGMAR1 (0.71) | SIGMAR1KDM4ELTA4HRECQLTDP1 | |
| SCHEMBL4484351 | 0.84 | SIGMAR1 (0.71) | SIGMAR1KDM4ERECQLTDP1HRH3 | |
| SCHEMBL5388793 | 0.84 | HRH3 (0.71) | SIGMAR1KDM4ELTA4HRECQLTDP1 | |
| SCHEMBL21004311 | 0.84 | SIGMAR1 (0.62) | SIGMAR1KDM4ERECQLTDP1HRH3 | |
| Hydrochloric Acid SCHEMBL3859180 | 0.83 | SIGMAR1 (0.74) | SIGMAR1KDM4ELTA4HRECQLTDP1 | |
| Hydrochloric Acid SCHEMBL6725877 | 0.82 | LTA4H (0.57) | SIGMAR1LTA4HHRH3USP2ALDH1A1 | |
| SCHEMBL15679705 | 0.82 | USP2 (0.82) | SIGMAR1LTA4HHRH3USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233799-B1 | DOPAMINE D2 RECEPTOR LIGANDS | BROAD INST INC (US) | 2021-05-19 | — | — | EP | disclosed |