Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23366836 | 0.81 | MAOA (0.40) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL23367181 | 0.75 | PIK3CD (0.32) | TDP1 | |
| SCHEMBL7271807 | 0.74 | KMT2A (0.45) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL23366824 | 0.74 | TDP1 (0.40) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL23366875 | 0.74 | EPHX1 (0.36) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL23367530 | 0.74 | TSHR (0.32) | TDP1LMNATSHRNFKB1 | |
| SCHEMBL842921 | 0.70 | TDP1 (0.52) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL8267374 | 0.69 | TDP1 (0.47) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL22624247 | 0.69 | MEN1 (0.49) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL23367211 | 0.69 | EPHX1 (0.39) | MAOAMAOBMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822265-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer AG (DE) | 2021-05-19 | — | — | EP | disclosed |