SCHEMBL23367181

SCHEMBL23367181

C=C(N)C(CN)(NC(C)=O)C(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.32
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23367231 0.79 PKM (0.37)
SCHEMBL23367183 0.75 MAOA (0.38) TDP1
SCHEMBL23366825 0.71 TDP1 (0.33) TDP1
SCHEMBL23367233 0.68 TDP1 (0.31) TDP1
SCHEMBL23366826 0.64 KDM4E (0.35)
SCHEMBL5693531 0.64 PAOX (0.34)
SCHEMBL23367398 0.63
SCHEMBL11032929 0.62
SCHEMBL9333241 0.61 CNR2 (0.33) PIK3CD
SCHEMBL2373187 0.61 PAOX (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3822265-A1 SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS Bayer AG (DE) 2021-05-19 EP disclosed