Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 9/20 | 0.41 |
| ▸ | CTSS | P25774 | 8/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17498475 | 0.80 | TDP1 (0.40) | KMT2AMEN1GAACTSKCTSS | |
| SCHEMBL27904493 | 0.77 | MEN1 (0.45) | KMT2AMEN1GAACTSKCTSS | |
| SCHEMBL16906203 | 0.76 | TDP1 (0.48) | KMT2AMEN1GAACTSKCTSS | |
| SCHEMBL1444341 | 0.74 | MEN1 (0.49) | KMT2AMEN1GAACTSKCTSS | |
| SCHEMBL22624247 | 0.74 | MEN1 (0.49) | KMT2AMEN1GAACTSKCTSS | |
| SCHEMBL14776705 | 0.74 | MEN1 (0.49) | KMT2AMEN1GAACTSKCTSS | |
| SCHEMBL23367183 | 0.74 | MAOA (0.38) | KMT2AMEN1GAACTSKCTSS | |
| SCHEMBL18428466 | 0.74 | CTSS (0.48) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL28136601 | 0.74 | CTSS (0.48) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL17627335 | 0.73 | CTSK (0.40) | KMT2AMEN1GAACTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |