Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23367607 | 0.76 | TSHR (0.36) | LMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL23367672 | 0.70 | KMT2A (0.33) | KMT2A | |
| SCHEMBL26464570 | 0.69 | LMNA (0.48) | LMNACYP1A2CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL24016011 | 0.69 | LMNA (0.48) | LMNACYP1A2CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL26464568 | 0.69 | LMNA (0.48) | LMNACYP1A2CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL25591396 | 0.68 | CYP1A2 (0.47) | LMNACYP1A2CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL25591392 | 0.68 | CYP1A2 (0.47) | LMNACYP1A2CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL25591394 | 0.68 | CYP1A2 (0.47) | LMNACYP1A2CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL24011237 | 0.67 | LMNA (0.49) | LMNACYP1A2CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL27404986 | 0.66 | KCNA5 (0.45) | LMNACYP1A2CYP3A4CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822265-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer AG (DE) | 2021-05-19 | — | — | EP | disclosed |