Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23367286 | 0.76 | LMNA (0.41) | L3MBTL1POLBLMNAALDH1A1 | |
| SCHEMBL23367672 | 0.73 | KMT2A (0.33) | — | |
| SCHEMBL24016010 | 0.68 | GUCY1B2 (0.44) | TSHRCETPL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL26464566 | 0.68 | GUCY1B2 (0.44) | TSHRCETPL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL25587522 | 0.67 | GUCY1B2 (0.43) | TSHRCETPL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL25587523 | 0.67 | GUCY1B2 (0.43) | TSHRCETPL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL25587521 | 0.67 | GUCY1B2 (0.43) | TSHRCETPL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL20840547 | 0.65 | SMN1; SMN2 (0.44) | L3MBTL1SMN1; SMN2GAAALDH1A1DPP4 | |
| SCHEMBL10057574 | 0.64 | HDAC3 (0.42) | L3MBTL1LMNAALDH1A1 | |
| SCHEMBL21316105 | 0.64 | SSTR4 (0.45) | IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021094434-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-05-20 | — | — | WO | disclosed |
| EP-3822265-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer AG (DE) | 2021-05-19 | — | — | EP | disclosed |