Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 10/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4048311 | 0.84 | SLC6A3 (0.55) | SMN1; SMN2ADRB3ADRB1ADRB2SLC6A2 | |
| SCHEMBL6320255 | 0.84 | SLC6A3 (0.55) | SMN1; SMN2ADRB3ADRB1ADRB2SLC6A2 | |
| Hydrochloric Acid SCHEMBL14126604 | 0.82 | HIF1A (0.54) | SMN1; SMN2ADRB3ADRB1ADRB2SLC6A2 | |
| Bromide SCHEMBL6286509 | 0.82 | SLC6A3 (0.53) | SMN1; SMN2ADRB3ADRB1ADRB2SLC6A2 | |
| SCHEMBL10886485 | 0.81 | ADRB1 (0.56) | SMN1; SMN2ADRB3ADRB1ADRB2LMNA | |
| SCHEMBL30488152 | 0.81 | ADRB1 (0.56) | SMN1; SMN2ADRB3ADRB1ADRB2LMNA | |
| SCHEMBL25272115 | 0.81 | ADRB1 (0.56) | SMN1; SMN2ADRB3ADRB1ADRB2LMNA | |
| SCHEMBL23384857 | 0.80 | ADRB3 (0.46) | SMN1; SMN2ADRB3ADRB1ADRB2SLC6A2 | |
| SCHEMBL23354845 | 0.80 | ADRB3 (0.52) | SMN1; SMN2ADRB3ADRB1ADRB2LMNA | |
| SCHEMBL6226534 | 0.80 | ADRB3 (0.52) | SMN1; SMN2ADRB3ADRB1ADRB2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822265-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer AG (DE) | 2021-05-19 | — | — | EP | disclosed |