SCHEMBL23367454

SCHEMBL23367454

O=C1C(=CC=C2N(C3CCCCC3)c3nc4ccccc4nc3N2C2CCCCC2)C(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.39
PKM P14618 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
OGFRL1 Q5TC84 12/20 0.37
OPRM1 P35372 11/20 0.37
OPRK1 P41145 11/20 0.37
OPRD1 P41143 10/20 0.37
GAA P10253 2/20 0.36
ALOX15 P16050 1/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ATM Q13315 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23338702 0.87 HCAR1 (0.37) KDM4EPKMNPSR1OGFRL1OPRM1
SCHEMBL23338693 0.86 ACVR1 (0.33) KDM4EPKMNPSR1OGFRL1OPRM1
SCHEMBL23338725 0.83 ALDH1A1 (0.38) KDM4EPKMNPSR1OGFRL1OPRM1
SCHEMBL25851063 0.79 MEN1 (0.37) KDM4EPKMNPSR1OGFRL1OPRM1
SCHEMBL25849866 0.78 ALDH1A1 (0.41) KDM4EPKMNPSR1GAAALOX15
SCHEMBL25849623 0.76 MEN1 (0.37) KDM4EPKMNPSR1OGFRL1OPRM1
SCHEMBL23338694 0.75 USP2 (0.36) KDM4ENPSR1ALDH1A1LMNARAB9A
SCHEMBL23337904 0.75 KDM4E (0.32) KDM4ENPSR1ALDH1A1LMNAKMT2A
SCHEMBL23337576 0.74 ALDH1A1 (0.36) KDM4ENPSR1OGFRL1OPRM1OPRK1
SCHEMBL23338696 0.73 KDM4E (0.33) KDM4ENPSR1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3823054-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM Corporation (JP) 2021-05-19 EP disclosed