SCHEMBL25849623

SCHEMBL25849623

CN1/C(=C\C=C2C(=O)c3cc4ccccc4cc3C2=O)N(C2CCCCC2)c2nc3ccccc3nc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
STAT3 P40763 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
OGFRL1 Q5TC84 13/20 0.36
OPRM1 P35372 11/20 0.36
OPRK1 P41145 11/20 0.36
GAA P10253 1/20 0.36
ALOX15 P16050 1/20 0.36
KDM4E B2RXH2 1/20 0.34
PKM P14618 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
OPRD1 P41143 9/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23338725 0.92 ALDH1A1 (0.38) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL25849612 0.85 ILF3 (0.39) MEN1KMT2AALDH1A1SMN1; SMN2KDM4E
SCHEMBL25849866 0.83 ALDH1A1 (0.41) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL25851063 0.81 MEN1 (0.37) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL23337907 0.81 ALDH1A1 (0.33) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL25849601 0.77 ILF3 (0.34) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL25849617 0.77 ILF3 (0.34) MEN1KMT2AALDH1A1SMN1; SMN2KDM4E
SCHEMBL25849614 0.77 ILF3 (0.34) MEN1KMT2AALDH1A1CYP1A2CYP3A4
SCHEMBL23338693 0.77 ACVR1 (0.33) ALDH1A1OGFRL1OPRM1OPRK1KDM4E
SCHEMBL23367454 0.76 KDM4E (0.39) MEN1KMT2AALDH1A1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed