SCHEMBL2336932

SCHEMBL2336932

CC(C)(C)[C@H](Nc1cccnc1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.50
NPC1 O15118 5/20 0.49
RAB9A P51151 5/20 0.49
PKM P14618 1/20 0.49
CFTR P13569 1/20 0.49
GOPC Q9HD26 1/20 0.49
NAMPT P43490 4/20 0.46
TSHR P16473 1/20 0.46
HTT P42858 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
KDM4E B2RXH2 3/20 0.44
LMNA P02545 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HIF1A Q16665 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2336939 1.00 FDPS (0.50) FDPSNPC1RAB9APKMCFTR
SCHEMBL8187155 0.82 NAMPT (0.50) FDPSNPC1RAB9APKMCFTR
SCHEMBL7936084 0.81 HCRTR2 (0.45) RAB9ATSHRSMN1; SMN2LMNAALDH1A1
SCHEMBL3047727 0.81 HCRTR2 (0.45) RAB9ATSHRSMN1; SMN2LMNAALDH1A1
SCHEMBL2159082 0.79 FDPS (0.51) FDPSNPC1RAB9APKMCFTR
SCHEMBL753183 0.79 FDPS (0.51) FDPSNPC1RAB9APKMCFTR
SCHEMBL2159076 0.79 FDPS (0.51) FDPSNPC1RAB9APKMCFTR
SCHEMBL44077 0.79 FDPS (0.54) FDPSNPC1RAB9APKMCFTR
SCHEMBL29417369 0.79 FDPS (0.54) FDPSNPC1RAB9APKMCFTR
SCHEMBL503440 0.79 FDPS (0.54) FDPSNPC1RAB9APKMCFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102216321-A Therapeutic antiviral peptides INTERMUNE INC 2011-10-12 CN disclosed
EP-2358736-A1 THERAPEUTIC ANTIVIRAL PEPTIDES Intermune, Inc. (US) 2011-08-24 EP disclosed
US-20100119479-A1 THERAPEUTIC ANTIVIRAL PEPTIDES INTERMUNE, INC. (US) 2010-05-13 US disclosed
US-20100119479-A1 THERAPEUTIC ANTIVIRAL PEPTIDES INTERMUNE, INC. (US) 2010-05-13 US disclosed
US-20100119479-A1 THERAPEUTIC ANTIVIRAL PEPTIDES INTERMUNE, INC. (US) 2010-05-13 US disclosed
WO-2010045266-A1 THERAPEUTIC ANTIVIRAL PEPTIDES INTERMUNE, INC. (US) 2010-04-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100119479-A1 THERAPEUTIC ANTIVIRAL PEPTIDES SARS1, VIP, MAVS FDPS 2404/4885NPC1 525/4885RAB9A 1692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.