SCHEMBL3047727

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7936084	1.00	HCRTR2 (0.45)	HCRTR2TDP1PDK1PDK2PDK3
	SCHEMBL1532145	0.85	HCRTR2 (0.43)	HCRTR2TDP1PDK1PDK2PDK3
	SCHEMBL2220609	0.83	MEN1 (0.45)	ALDH1A1LMNAALOX12RECQLMAPT
	SCHEMBL2220603	0.83	MEN1 (0.45)	ALDH1A1LMNAALOX12RECQLMAPT
	SCHEMBL11204276	0.83	PDK1 (0.46)	TDP1PDK1PDK2PDK3PDK4
	SCHEMBL12401982	0.83	MEN1 (0.49)	TDP1HSD17B10ALDH1A1LMNAL3MBTL1
	SCHEMBL30589675	0.82	CA12 (0.44)	TDP1PDK1PDK2PDK3PDK4
	SCHEMBL3042876	0.81	MMP2 (0.50)	TSHRALDH1A1ATMCA12CA9
	SCHEMBL2336932	0.81	FDPS (0.50)	TSHRCYP3A4ALDH1A1LMNAHPGD
	SCHEMBL2336939	0.81	FDPS (0.50)	TSHRCYP3A4ALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.