Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 3/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15103566 | 0.94 | FAAH (0.42) | HTR4TMEM97SIGMAR1HTR3ADRD4 | |
| SCHEMBL2335207 | 0.94 | FAAH (0.42) | HTR4TMEM97SIGMAR1HTR3ADRD4 | |
| SCHEMBL15103575 | 0.90 | HTR4 (0.43) | HTR4DRD4FAAHACHE | |
| Hydrochloric Acid SCHEMBL2337272 | 0.89 | HTR4 (0.43) | HTR4DRD4FAAHACHE | |
| SCHEMBL15103540 | 0.89 | HTR4 (0.56) | HTR4 | |
| SCHEMBL2337246 | 0.88 | DRD4 (0.51) | TMEM97SIGMAR1DRD4 | |
| SCHEMBL3304360 | 0.85 | HTR4 (0.43) | HTR4TMEM97SIGMAR1HTR3ACNR2 | |
| SCHEMBL2337032 | 0.85 | ACHE (0.43) | HTR4DRD4FAAHACHE | |
| Hydrochloric Acid SCHEMBL3297629 | 0.85 | HTR4 (0.43) | HTR4TMEM97SIGMAR1HTR3ACNR2 | |
| SCHEMBL2333495 | 0.84 | FAAH (0.43) | HTR4SIGMAR1DRD4FAAHACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358702-B1 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK BIOPHARMACEUTICALS CO LTD (KR) | 2013-07-17 | — | — | EP | claimed |
| EP-2358702-A2 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK Holdings Co., Ltd. (KR) | 2011-08-24 | — | — | EP | claimed |
| WO-2010044585-A2 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK HOLDINGS CO., LTD. (KR) | 2010-04-22 | — | — | WO | claimed |
| EP-2358702-B1 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK BIOPHARMACEUTICALS CO LTD (KR) | 2013-07-17 | — | — | EP | disclosed |
| WO-2010044585-A2 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK HOLDINGS CO., LTD. (KR) | 2010-04-22 | — | — | WO | disclosed |