Tetrahydrofuran

Tetrahydrofuran

SCHEMBL2336993

C1CCOC1.COCCOCCOCCOCCOC.COCCOCCOCCOCCOC

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
CA2 P00918 1/20 0.33
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL28609324 1.00 ALDH1A1 (0.42) ALDH1A1CA2TDP1
Tetrahydrofuran SCHEMBL310535 1.00 ALDH1A1 (0.42) ALDH1A1CA2TDP1
SCHEMBL11713823 0.97 ALDH1A1 (0.40) ALDH1A1CA2TDP1
SCHEMBL8859291 0.97 ALDH1A1 (0.40) ALDH1A1CA2TDP1
Tetrahydrofuran SCHEMBL2361115 0.92 ALDH1A1 (0.50) ALDH1A1TDP1
Dioxane SCHEMBL8149387 0.89 CA2 (0.35) CA2TDP1
Dioxane SCHEMBL10324821 0.89 CA2 (0.35) CA2TDP1
Dioxane SCHEMBL3104036 0.89 CA2 (0.35) CA2TDP1
Tetrahydrofuran SCHEMBL5235661 0.89 ALDH1A1 (0.47) ALDH1A1TDP1
SCHEMBL7703561 0.89 ALDH1A1 (0.47) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2358831-A1 AMPHOTERIC POYURETHANE DISPERSANTS AND THEIR USE IN INKJET INKS E. I. du Pont de Nemours and Company (US) 2011-08-24 EP disclosed
EP-2220177-A1 AQUEOUS INKJET INKS WITH IONICALLY STABILIZED DISPERSIONS AND POLYURETHANE INK ADDITIVES E. I. du Pont de Nemours and Company (US) 2010-08-25 EP disclosed
EP-2220137-A1 UREA-TERMINATED POLYURETHANE DISPERSANTS E. I. du Pont de Nemours and Company (US) 2010-08-25 EP disclosed
WO-2010068871-A1 AMPHOTERIC POYURETHANE DISPERSANTS AND THEIR USE IN INKJET INKS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-17 WO disclosed
WO-2009076386-A1 AQUEOUS INKJET INKS WITH IONICALLY STABILIZED DISPERSIONS AND POLYURETHANE INK ADDITIVES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-18 WO disclosed
WO-2009076381-A1 UREA-TERMINATED POLYURETHANE DISPERSANTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-18 WO disclosed