Tetrahydrofuran

Tetrahydrofuran

SCHEMBL310535

C1CCOC1.COCCOCCOC

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
CA2 P00918 1/20 0.33
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL28609324 1.00 ALDH1A1 (0.42) ALDH1A1CA2TDP1
Tetrahydrofuran SCHEMBL2336993 1.00 ALDH1A1 (0.42) ALDH1A1CA2TDP1
SCHEMBL11713823 0.97 ALDH1A1 (0.40) ALDH1A1CA2TDP1
SCHEMBL8859291 0.97 ALDH1A1 (0.40) ALDH1A1CA2TDP1
Tetrahydrofuran SCHEMBL2361115 0.92 ALDH1A1 (0.50) ALDH1A1TDP1
Dioxane SCHEMBL8149387 0.89 CA2 (0.35) CA2TDP1
Dioxane SCHEMBL10324821 0.89 CA2 (0.35) CA2TDP1
Dioxane SCHEMBL3104036 0.89 CA2 (0.35) CA2TDP1
Tetrahydrofuran SCHEMBL5235661 0.89 ALDH1A1 (0.47) ALDH1A1TDP1
SCHEMBL7703561 0.89 ALDH1A1 (0.47) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117117331-A Alkali metal sulfur battery electrolyte, preparation method thereof and alkali metal sulfur secondary battery comprising same 天津工业大学 2023-11-24 CN claimed
EP-0900180-B1 PROCESS FOR THE PREPARATION OF FLUORO COMPOUNDS FROM THE CORRESPONDING AMINES RHODIA LTD (GB) 2002-03-20 EP claimed
US-6179970-B1 COMPOUNDS CONTAINING PRIMARY AMINO GROUP ARE CONVERTED INTO COMPOUNDS CONTAINING FLUORINE IN PLACE OF AMINO GROUP BY REACTION OF AMINO COMPOUND WITH HYDROGEN FLUORIDE AND NITROSATING REAGENT USING ULTRASOUND OR MICROWAVE ENERGY RHODIA LIMITED (GB) 2001-01-30 US claimed
EP-0900180-A1 PROCESS FOR THE PREPARATION OF FLUORO COMPOUNDS FROM THE CORRESPONDING AMINES Rhodia Limited (GB) 1999-03-10 EP claimed
WO-1997041083-A1 PROCESS FOR THE PREPARATION OF FLUORO COMPOUNDS FROM THE CORRESPONDING AMINES RHODIA LIMITED (GB) 1997-11-06 WO claimed
US-5279820-A Termiticides DAIKIN INDUSTRIES, LTD. (JP) 1994-01-18 US claimed
CN-117117331-A Alkali metal sulfur battery electrolyte, preparation method thereof and alkali metal sulfur secondary battery comprising same 天津工业大学 2023-11-24 CN disclosed
CN-113498562-A Electrolyte solution, electrochemical device, and electronic device 宁德新能源科技有限公司 2021-10-12 CN disclosed
CN-110760709-B Preparation method of graphene reinforced magnesium composite material 河北工业大学 2021-07-27 CN disclosed
CN-110760709-A Preparation method of graphene reinforced magnesium composite material 河北工业大学 2020-02-07 CN disclosed
CN-105390617-B Organic electroluminescent device 柯尼卡美能达株式会社 2018-06-01 CN disclosed
US-8110689-B2 Benzanilides with insecticidal activity BAYER CROPSCIENE AG (DE) 2012-02-07 US disclosed
US-8093421-B2 Stereoselective one step fluorination process for the preparation of 2-flouropropionate BAYER CROPSCIENCE AG (DE) 2012-01-10 US disclosed
US-4886817-A Imidazolidinones as brain activators TANABE SEIYAKU CO., LTD. (JP) 1989-12-12 US disclosed
EP-0268229-A2 Imidazolidinone compounds, processes for preparation thereof, compositions comprising such compounds, and the use of such compounds for the manufacture of medicaments having therapeutic value TANABE SEIYAKU CO., LTD. (JP) 1988-05-25 EP disclosed
EP-0260121-A2 Inosose derivatives, production and use thereof Takeda Chemical Industries, Ltd. (JP) 1988-03-16 EP disclosed
EP-0236140-A2 Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1987-09-09 EP disclosed
EP-0121847-B1 2,2-DIMETHYL-3-(2-HALOVINYL)CYCLOPROPANE CARBOXYLATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES BAYER AG (DE) 1987-01-14 EP disclosed
EP-0121847-A2 2,2-dimethyl-3-(2-halovinyl)cyclopropane carboxylates, process for their preparation and their use as pesticides BAYER AG (DE) 1984-10-17 EP disclosed
US-4018806-A FRACTIONAL CRYSTALLIZATION THE PROCTER & GAMBLE COMPANY (US) 1977-04-19 US disclosed