Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI | P10646 | 4/20 | 0.53 |
| ▸ | FLT1 | P17948 | 1/20 | 0.53 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | KRAS | P01116 | 1/20 | 0.50 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.48 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | EHD1 | Q9H4M9 | 3/20 | 0.48 |
| ▸ | CIB1 | Q99828 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrothricin SCHEMBL23370285 | 1.00 | TFPI (0.53) | TFPIFLT1PCSK9HDAC4KRAS | |
| SCHEMBL17133082 | 0.95 | FLT1 (0.57) | TFPIFLT1PCSK9HDAC4KRAS | |
| Tyrocidine A SCHEMBL16418974 | 0.92 | HDAC4 (0.55) | TFPIFLT1PCSK9HDAC4KRAS | |
| Tyrocidine A SCHEMBL12131172 | 0.92 | HDAC4 (0.55) | TFPIFLT1PCSK9HDAC4KRAS | |
| Tyrocidine A SCHEMBL14399288 | 0.92 | HDAC4 (0.55) | TFPIFLT1PCSK9HDAC4KRAS | |
| Loloatin A SCHEMBL6050533 | 0.91 | FLT1 (0.56) | TFPIFLT1PCSK9HDAC4ITGB3 | |
| Laterocidin SCHEMBL29824961 | 0.91 | FLT1 (0.56) | TFPIFLT1PCSK9HDAC4ITGB3 | |
| Tyrocidine A1 SCHEMBL31412201 | 0.90 | HDAC4 (0.56) | TFPIFLT1PCSK9HDAC4KLK5 | |
| Tyrocidine A1 SCHEMBL29489412 | 0.90 | HDAC4 (0.56) | TFPIFLT1PCSK9HDAC4KLK5 | |
| SCHEMBL31412206 | 0.88 | TFPI (0.50) | TFPIFLT1PCSK9HDAC4KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210144998-A1 | COMPOSITIONS AND METHODS FOR TREATING HUANGLONGBING DISEASE IN CITRUS | NEW LIFE CROP SCIENCES LLC | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210144998-A1 | COMPOSITIONS AND METHODS FOR TREATING HUANGLONGBING DISEASE IN CITRUS | PNPO, G6PD, AGXT | TFPI 2918/4885FLT1 427/4885PCSK9 470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.