Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.64 |
| ▸ | NPC1 | O15118 | 10/20 | 0.64 |
| ▸ | RAB9A | P51151 | 10/20 | 0.64 |
| ▸ | PKM | P14618 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | STAT1 | P42224 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27522241 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9APKMPOLB | |
| SCHEMBL8359829 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9APKMPOLB | |
| SCHEMBL5029316 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9APKMPOLB | |
| SCHEMBL14579827 | 0.78 | MAPK1 (0.59) | SMN1; SMN2NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL5028569 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9APKMPOLB | |
| SCHEMBL13996754 | 0.77 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9APKMPOLB | |
| SCHEMBL24083505 | 0.77 | FADS1 (0.52) | SMN1; SMN2NPC1RAB9ALMNAMEN1 | |
| SCHEMBL18118621 | 0.76 | RAB9A (0.69) | SMN1; SMN2NPC1RAB9APKMPOLB | |
| SCHEMBL9205677 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9APKMPOLB | |
| SCHEMBL23370811 | 0.76 | KMT2A (0.54) | SMN1; SMN2NPC1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3919474-B1 | HBV INHIBITOR AND USE THEREOF | XIAN XINTONG PHARMACEUTICAL RES CO LTD (CN) | 2023-10-11 | — | — | EP | disclosed |
| EP-4245372-A2 | HBV INHIBITOR AND USE THEREOF | Xi'An Xintong Pharmaceutical Research Co., Ltd. (CN) | 2023-09-20 | — | — | EP | disclosed |
| US-20220184035-A1 | HBV INHIBITOR AND ITS USE | XI'AN XINTONG PHARMACEUTICAL RESEARCH CO., LTD. (CN) | 2022-06-16 | — | — | US | disclosed |
| EP-3919474-A1 | HBV INHIBITOR AND USE THEREOF | Xi'An Xintong Pharmaceutical Research Co., Ltd. (CN) | 2021-12-08 | — | — | EP | disclosed |
| WO-2021093172-A1 | HBV INHIBITOR AND USE THEREOF | 西安新通药物研究有限公司 | 2021-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220184035-A1 | HBV INHIBITOR AND ITS USE | HAVCR2, HDGF, ZC3HAV1 | SMN1; SMN2 4828/4885NPC1 291/4885RAB9A 929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.