Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335503 | 0.92 | LPAR1 (0.44) | ALDH1A1LPAR1HTTPKMKDM4E | |
| SCHEMBL3702406 | 0.92 | ALDH1A1 (0.36) | ALDH1A1LPAR1L3MBTL1ALOX15CRHBP | |
| SCHEMBL2335059 | 0.87 | LPAR1 (0.41) | ALDH1A1LPAR1L3MBTL1CYP4Z1PKM | |
| SCHEMBL3705980 | 0.85 | ALDH1A1 (0.37) | ALDH1A1LPAR1L3MBTL1ALOX15CRHBP | |
| SCHEMBL2338529 | 0.84 | LPAR1 (0.44) | ALDH1A1LPAR1HTTPKMKDM4E | |
| SCHEMBL2635999 | 0.82 | ABCC3 (0.39) | LPAR1 | |
| SCHEMBL2337994 | 0.82 | HDAC6 (0.43) | HDAC4HDAC6SYKMAPT | |
| SCHEMBL2336265 | 0.82 | LPAR1 (0.41) | ALDH1A1LPAR1L3MBTL1ALOX15CRHBP | |
| SCHEMBL3706822 | 0.82 | ALDH1A1 (0.37) | ALDH1A1LPAR1L3MBTL1ALOX15CRHBP | |
| SCHEMBL2636202 | 0.81 | LPAR1 (0.45) | ALDH1A1LPAR1PKMKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358688-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | Amira Pharmaceuticals, Inc. (US) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010077883-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |